DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5687 and Slc5a3

DIOPT Version :9

Sequence 1:	NP_001286910.1	Gene:	CG5687 / 38255	FlyBaseID:	FBgn0035293	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_059087.2	Gene:	Slc5a3 / 53881	MGIID:	1858226	Length:	718	Species:	Mus musculus

Alignment Length:	559	Identity:	125/559 - (22%)
Similarity:	223/559 - (39%)	Gaps:	96/559 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 KATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSEMSIFPVTLSLTTSFITAIELL 157
            :|.....|..::....::.:.||.|..:.....:.|..||.|..|:...:..||..|.|.:...:
Mouse     2 RAVLEAADIAVVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFI 66

  Fly   158 GNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRF-GKEIRILGAVLYV 221
            |........|..........::::.:...:|.|||.:..:.:..|||..|| |..|::..|.|.:
Mouse    67 GLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSL 131

  Fly   222 IQMCF-YTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSL 285
            :...| ..:|.:.:.|:.:.::.|.:..::|:|:..:....:..||:.||:..|:.||.::.:..
Mouse   132 LLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGA 196

  Fly   286 VLIVGLGCFYSGNPIQV---FQTASD-------------------HNRLEFFNMDPDPTTRHTVW 328
            :.::.:.....|...:|   :..||.                   |.:.....|..|||.....|
Mouse   197 LTLMVISMVKIGGFEEVKRRYMLASPDVASILLKYNLSNTNACMVHPKANALKMLRDPTDEDVPW 261

  Fly   329 SVVIGG-----FFYWTSLFCTNQASVQKCMSLKSLRLAK---IALGFAIIGLIVVFLLNFYTGLM 385
            ...|.|     .:||    |.:|..||:.::.|::..||   :..||  :.|:.:|:: ...|::
Mouse   262 PGFILGQTPASVWYW----CADQVIVQRVLAAKNIAHAKGSTLMAGF--LKLLPMFII-VVPGMI 319

  Fly   386 VFTHYAD---------CDPLTAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASA 441
            ....:||         |..:...|...::...|..|:....  ..:.|:.:|.:.||.:..:.|.
Mouse   320 SRIVFADEIACINPEHCMQVCGSRAGCSNIAYPRLVMTLVP--VGLRGLMMAVMIAALMSDLDSI 382

  Fly   442 LNSLSAVTCEDL--LVNGMNIKISPEKGATYAKWMSLGFGIASFGLV-------FIVEHLGGVLQ 497
            .||.|.:...|:  |:         .|.|:..:.|.:|....:|.:|       .|||..||  |
Mouse   383 FNSASTIFTLDVYKLI---------RKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGG--Q 436

  Fly   498 ATLTLNGLIGGVT---LGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVVAQIVS-------VE 552
            ..|.:..:...:|   ..||:|.|..|:.|.:||||||:....|    |.|..|::       .:
Mouse   437 MYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL----GAVRLILAFTYRAPECD 497

  Fly   553 QPALPTSIDKCDCH-----------VNMTNIIGSLLTEP 580
            ||.......| |.|           ..:..:|.||||.|
Mouse   498 QPDNRPGFIK-DIHYMYVATALFWITGLITVIVSLLTPP 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	124/553 (22%)
Slc5a3	NP_059087.2	SLC5sbd_SMIT	9..718	CDD:271382	124/552 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810