DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5687 and salt

DIOPT Version :9

Sequence 1:	NP_001286910.1	Gene:	CG5687 / 38255	FlyBaseID:	FBgn0035293	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_651889.3	Gene:	salt / 43742	FlyBaseID:	FBgn0039872	Length:	622	Species:	Drosophila melanogaster

Alignment Length:	598	Identity:	170/598 - (28%)
Similarity:	309/598 - (51%)	Gaps:	48/598 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 FSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSE-MSIFPVTLSLTTSFITAIELLGN 159
            ||..||::...||..|.|||:::|||.|..:::.|:|.|.: |...||.:||.:|.::.:.::..
  Fly    25 FSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSV 89

  Fly   160 PSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKEIRILGAVLYVIQM 224
            |:|.|..|...:.:|..||:.:||.:.|..|:::...:::|||||.:||.|..|.|..:.:::..
  Fly    90 PAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFILNQ 154

  Fly   225 CFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVLIV 289
            .....|.:..|::|.|:.||.:..:...::..:||||:..||:||||..|..|.:|:.:|:||:.
  Fly   155 FLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVLVA 219

  Fly   290 GLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVIGGFFYWTSLFCTNQASVQKCMS 354
            .||...:|....|.:.|::..|.: |:...||..|.|..|.:..|...||.....:|:.||:.:|
  Fly   220 ILGTSNTGGITNVLENAAEGGRFD-FSFGIDPRLRLTFISGMASGLLMWTGKLGLDQSCVQRIVS 283

  Fly   355 LKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVINTYEHI 419
            |.|...||..|..|.:|.:::.....:||:::|.:|..|||:.||.:|..|:|:|:::.:...|:
  Fly   284 LPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQDIMGHM 348

  Fly   420 SSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKGATYAKWMSLGFGIASFG 484
            ..:.|:|::.:|:|||.:::::|||.:.|...|.:...:|  .|..|.....|.:.:..|.....
  Fly   349 MGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRIN--HSEAKANATMKLVIVVMGAYCIV 411

  Fly   485 LVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVVAQI- 548
            ..|||::...::|...|:.|:..|..:|:|.||:...:.|.|.|..|...|..:::::.:..|:
  Fly   412 GGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQMN 476

  Fly   549 ---VSVEQPALPTSIDKCDC-----------HVNMTNIIGSLLTEPLEVIEE--GGFTS---WPI 594
               ..::...||..:|:|:.           :.|:|| :|:.....||..:|  ..|.|   :.|
  Fly   477 FKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTN-VGTTAIPSLEAPKELTTAFDSNRDFSI 540

  Fly   595 FRLSYMWYSMIGCLLTVFLGWFISLI----IDFIQRRN-----------------VLKITGKDID 638
            :..|:.||.::|.|| || .|.|.:.    :|..:::|                 ||::....:.
  Fly   541 YDTSFYWYKVLGALL-VF-AWAIPMSYVWPLDKEEKQNPKLYSPFVRSMLNKPSPVLELEELPLK 603

  Fly   639 NPAVSEEIFKSDS 651
            .|...|:|.:.::
  Fly   604 TPLSEEQIKEKEN 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	161/541 (30%)
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	161/543 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I370
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	9	8.970