DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5687 and CG7720

DIOPT Version :9

Sequence 1:	NP_001286910.1	Gene:	CG5687 / 38255	FlyBaseID:	FBgn0035293	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_001163649.1	Gene:	CG7720 / 42257	FlyBaseID:	FBgn0038652	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	151/551 - (27%)
Similarity:	276/551 - (50%)	Gaps:	31/551 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 GYDYVILLGMLVISLGIGIFYG--FFQKGGSSSNEFLLGS-EMSIFPVTLSLTTSFITAIELLGN 159
            |:||::.:..:.::: :|..:.  |.:|...|..:::..: .:||..|.:|:....:....:||.
  Fly     9 GWDYLMFVLFIALTV-LGPLWKRIFGKKKERSKADYVFATGGVSIVAVMISIARGTLGVRSVLGY 72

  Fly   160 PSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRF-GKEIRILGAVLYVIQ 223
            |||:|::|:....|:..|:...|:...:|.|:||.:.:||.|:|:.:|| .:.:|.|.:..|:::
  Fly    73 PSELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRFKSRTVRCLASATYIVR 137

  Fly   224 MCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVLI 288
            ......:.|..|::|||...|:....::..:.|:|:|::..||:||.:.||..|...:.|..|.:
  Fly   138 QICNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQTVTILVVTVAV 202

  Fly   289 VGLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVIGGFFYWTSLFCTNQASVQKCM 353
            ...|...:|...:|:|...|:.||.|:|...|.|.|....|..:|..|...|.....|..:|:.:
  Fly   203 CIQGTISTGGVKKVYQLNRDNGRLNFWNFTGDMTVRVDTTSAWLGQLFMSLSQIGCQQNFMQRYV 267

  Fly   354 SLKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVINTYEH 418
            |||||:..:..:...:..:...|.:::.:|:::::.|.:|||...|.|...|::||::|.:....
  Fly   268 SLKSLKQVRRVMLTNVPLVFFFFSISWISGMVIYSTYINCDPYAEGYIKKPDEILPFFVEDQLGF 332

  Fly   419 ISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIK-ISPEKGATYAKWMSLGFGIAS 482
            :....|||:|.:|..:|..:.|.||||:.|..||.:......| :|.::.....|.:::..|:..
  Fly   333 LPGFVGIFMATLFNGALCMMVSNLNSLATVIWEDFISQLPKFKGLSDKQQLRILKSITVVCGLII 397

  Fly   483 FGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVVAQ 547
            .|:.|.|..|.||::::|.:.....|..||.|:|.:....||.||...|.:.:.|.|:::.....
  Fly   398 MGVAFGVGLLAGVIESSLLVFSATSGPLLGCFILAMMVPIANWKGTSAGMVTACAFVLWIIGGGM 462

  Fly   548 IVSVEQPALPTSIDKCD----------------------CHVNMTNIIGSLL-TEPLEVIEEGGF 589
            .|:.:.|.||||.|.|.                      .|..:.....|.: |:|....|..|.
  Fly   463 TVTKDNPLLPTSTDGCTNDTFAQSIGKPIVEQGQMPWLLSHTPIDGFNQSFVPTQPTIAPERSGL 527

  Fly   590 TSWPIFRLSYMWYSMIGCLLTVFLGWFISLI 620
            .::  :.:|:|:||:||..|||.:|..|||:
  Fly   528 ETF--YSISFMYYSLIGTALTVIIGTVISLL 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	149/548 (27%)
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	149/548 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970