Protein Alignment CG5687 and slc5a2

DIOPT Version :9

• Sequence 1: NP_001286910.1
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_998091.1
• Gene: slc5a2 / 405862
• ZFINID: ZDB-GENE-040426-2498
• Length: 662
• Species: Danio rerio
• Alignment Length: 623
• Identity: 132/623 - (21%)
• Similarity: 242/623 - (38%)
• Gaps: 155/623 - (24%)

  Fly    58 EHVEFDNAATLLLRAFKNQQIPASAELEECSAPSHKATFSGYDYVILLGMLVISLGIGIFYGFFQ 122
            :||..:|||.:                                .||::..||: :.:||:..|..
Zfish     7 KHVTINNAADI--------------------------------SVIIIYFLVV-IAVGIWSTFRT 38

  Fly   123 KGGSSSNEFLLGSEMSIFPVTLSLTTSFITAIELLGNPSEMYFQG---------TQFVLIVIPMV 178
            ..|:....||.|..|..:||..||..|.|.:...:|........|         ..|:::::..|
Zfish    39 NRGTVGGYFLAGRTMVWWPVGTSLFASNIGSGHFVGLAGTAAASGIAVGGFEWNALFIVLLLGWV 103

  Fly   179 IVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKE-----IRILGAVLYVIQMCFYTAVAV--LAPA 236
                     |.|:|....:.:..:||..|||..     :.|:...||:     :|.::|  .:.|
Zfish   104 ---------FVPVYLTAGVITMPQYLKKRFGGSRISLYLSIISLFLYI-----FTKISVDMFSGA 154

  Fly   237 IALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVLIVGLGCFY------ 295
            :.:.:|.|.:..:||:.:..:...|:..||:.|::..|:.|..|:.....:::|.. ||
Zfish   155 VFIQQALGWNIYVAVIALLCITALYTVTGGLAALMYTDTVQTFVIIAGAFVLMGFS-FYEVGGYS 218

  Fly   296 -------SGNPIQVFQ-TASDHN--------RLEFFNMDPDPTTRHTVW-SVVIG----GFFYWT 339
                   |..|.|... ..:::|        |.:.|::..||||....| .|:.|    |.:||
Zfish   219 ALLEKYNSSLPSQTLSLNPNEYNISQHCYMPREDAFHLLRDPTTGDLPWPGVIFGIAIIGSWYW- 282

  Fly   340 SLFCTNQASVQKCMSLKSLRLAK---IALGFAIIGLIVVFLLNFYTGLMVFTHYAD--------- 392
               ||:|..||:|::.:||...|   |..|:  :.|:.:||:.| .|::....|.|
Zfish   283 ---CTDQVIVQRCLAARSLTHVKAGCILCGY--LKLLPMFLMVF-PGMISRVLYPDDVGCVEKSV 341

  Fly   393 CDPLTAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNG 457
            |:.:....:..::...|..|::...  :.:.|:.:|.:.||.:.::||..||.|.:...|:..
Zfish   342 CNKVCGTEVGCSNIAYPKLVVSVMP--TGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIWT-- 402

  Fly   458 MNIKISP-----EKGATYAKWMSLGFGIASFGL-VFIVEHLGGVLQATLTLNGLIGGVTLGLFVL 516
               :|.|     |.......|:....||::..: |......|.:.....::...:......:|.|
Zfish   403 ---RIRPQARDKELMVVGRVWILCIVGISTCWIPVVQAAQSGQLFDYIQSVTSYLAPPIAAVFFL 464

  Fly   517 GIACKQANTKGAFYGGLLSLALVIFVGVVAQIVSVEQPAL-PTSIDKCDCHVNMTNIIGSLLTEP 580
            .|..|:.|..|||: ||:...::....:|.:.|......| |::..|..|.|:
Zfish   465 AIFVKRVNESGAFW-GLMGGLVMGLCRMVPEFVFGSGSCLKPSNCPKVICGVH------------ 516

  Fly   581 LEVIEEGGFTSWPIFRLSYMWYSMIGCLLTVFLGWFIS 618
                              |::::::....|..|..|:|
Zfish   517 ------------------YLYFAILLFFCTAILVLFVS 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	127/582 (22%)
slc5a2	NP_998091.1	SLC5sbd_SGLT2	15..662	CDD:212056	128/615 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910