Protein Alignment CG5687 and slc5a8

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_001351880.1
• Gene: slc5a8 / 394505
• XenbaseID: XB-GENE-479634
• Length: 620
• Species: Xenopus tropicalis
• Alignment Length: 617
• Identity: 203/617 - (32%)
• Similarity: 340/617 - (55%)
• Gaps: 45/617 - (7%)

  Fly    90 PSHKATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGS-EMSIFPVTLSLTTSFITA 153
            |.:..:|:.:|||:...||:||..|||:|.|...|..:|.:||:|. .|:..||.||||.||::|
 Frog     4 PGNIGSFTVWDYVVFALMLLISAVIGIYYAFAGGGQKTSKDFLMGGRSMTAVPVALSLTASFMSA 68

  Fly   154 IELLGNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKEIRILGAV 218
            :.:||.|:|:|..|:.|.:......||:.::.::|.|:::::.:||.||||.:||.|.:|:||.:
 Frog    69 VTVLGTPAEVYRFGSMFSIFAFTYAIVVVISSEVFLPVFYRLGITSTYEYLELRFNKFVRLLGTI 133

  Fly   219 LYVIQMCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAV 283
            |::||...||.:.:.|||:||::.||.|...|||...|||.||.:.||:||||..|.||..::..
 Frog   134 LFIIQTVLYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTMGGLKAVVWTDVFQVGIMVA 198

  Fly   284 SLVLIVGLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVIGGFFYWTSLFCTNQAS 348
            ....::.......|....:...:...:||.|::..|:|..||:.|::|:||.|.||.::..||:.
 Frog   199 GFSSVIIRAVVVQGGIGPILNDSYYGDRLNFWDFTPNPLQRHSFWTIVVGGTFTWTGIYGVNQSQ 263

  Fly   349 VQKCMSLKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVI 413
            ||:.::.|:...||::|...::||..:......:||.:::.|.||||.||..:||.|||:||..:
 Frog   264 VQRYIACKTRFQAKLSLYINLLGLWAILACAVLSGLAMYSIYKDCDPWTAQFVSAPDQLMPYLSL 328

  Fly   414 NTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKGATYAKWMSLGF 478
            :.......:.|:||:..::.:|.||:|::|:|:|||.|||:..... .:|..|.:..:|..||.:
 Frog   329 DILRDYPGLPGLFVSCAYSGTLSTVSSSINALAAVTVEDLIKPYFR-SLSETKMSWISKGTSLIY 392

  Fly   479 GIASFGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVG 543
            |.....:..:...:||:|||.|::.|::||..||||.|||.....|:.||..|.|...|:.::||
 Frog   393 GAICIAMAGLASLMGGLLQAALSIFGMVGGPLLGLFALGIIFPFVNSLGAVIGLLSGFAISLWVG 457

  Fly   544 VVAQI----VSVEQPALPTSIDKCD-----------CHVNMTNIIGSLLTEPLEVIEEGGFTSWP 593
            :.:||    .|...|. |.|::.|:           ....||.:|..:.:.| |:.:     ||
 Frog   458 IGSQIYPPTASSSLPK-PLSLEGCNFTSFESNWTTTVMPMMTTLIPEVSSRP-ELAD-----SW- 514

  Fly   594 IFRLSYMWYSMIGCLLTVFLGWFISLII---------DFI------QRRNVL----KITGKDIDN 639
             :.|||:::|.:|.::.|.:|...||:.         ||:      ...|||    |..|::...
 Frog   515 -YSLSYLYFSTLGTIVAVVVGVIASLLSGGLKQNVNRDFLLTSQDFSYLNVLFSNCKKKGQEEKV 578

  Fly   640 PAVSEEIFKSDSQVQYTTTTVIGDPRELTSDE 671
            ..::.::..:|:.:...|.....:..|::|.|
 Frog   579 EVLNWKMRSTDTDMDQGTDNPAFNHMEMSSTE 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	188/536 (35%)
slc5a8	NP_001351880.1	SLC5sbd_SMCT1	7..547	CDD:271402	190/549 (35%)