Protein Alignment CG5687 and slc5a1

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_956975.1
• Gene: slc5a1 / 393654
• ZFINID: ZDB-GENE-040426-1524
• Length: 658
• Species: Danio rerio
• Alignment Length: 553
• Identity: 138/553 - (24%)
• Similarity: 238/553 - (43%)
• Gaps: 106/553 - (19%)

  Fly   102 VILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSEMSIFPVTLSLTTSFI-----TAIELLGNPS 161
            ||::..||: |.:|::........:....||.|..|..:|:..||..|.|     ..|...|..:
Zfish    31 VIVIYFLVV-LAVGVWAMVRTNRATVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGIAGTGAAA 94

  Fly   162 EMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRF-GKEIRILGAVLYVIQMC 225
            .:...|.::..:|:  ||::.   .:|.|||.|..:.:..|||..|| |:.|||   .|.|:.:|
Zfish    95 GIAIGGFEWNALVV--VIILG---WLFVPIYIKAGVVTMPEYLKKRFGGQRIRI---YLSVLSLC 151

  Fly   226 FYT----AVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLV 286
            .|.    :..:.|.||.:::|.||:..:|||::.::...|:..||:.||:..|:.|..::.|...
Zfish   152 LYVFTKISADMFAGAIFINQALGLNIYLAVVILLLITALYTVTGGLAAVIYTDTLQTIIMVVGSF 216

  Fly   287 LIVGLGCFYSGNPIQVFQTASDH-------------------NRLEFFNMDPDPTTRHTVWSVVI 332
            :::|    ::.|.:..::...|.                   .|.:.|::..||......|..::
Zfish   217 ILMG----FAFNKVGGYENFRDSYMTAIPSVIGTNISESCYTPRADSFHIFRDPINGDLPWPGLL 277

  Fly   333 GGF-----FYWTSLFCTNQASVQKCMSLKSLRLAK---IALGFAIIGLIVVFLLNFYTGLMVFTH 389
            .|.     :||    ||:|..||:|:|.|:|...|   |..|:  :.|:.:||:.| .|::....
Zfish   278 FGLTIQAGWYW----CTDQVIVQRCLSAKNLSHVKAGCILCGY--LKLLPMFLMVF-PGMISRVL 335

  Fly   390 YAD---------CDPLTAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASALNSL 445
            |.|         |..:....:..|:...|..|::...  :.:.|:.::.:.|:.:.::.|..||.
Zfish   336 YPDEIACVDPDECKAVCGAEVGCTNIAYPKLVVDLMP--NGLRGLMLSVMLASLMSSLTSIFNSA 398

  Fly   446 SAVTCEDLLVNGMNIKISP---EKGATYA--KWMSLGFGIASFGLVFIVE--HLGGVLQATLTLN 503
            |.:...|:..     ||.|   ||....|  .:|.|..|| |...:.||:  ..|.:.....::.
Zfish   399 STLFTMDIYT-----KIRPKAKEKELMIAGRLFMLLLIGI-SIAWIPIVQTAQSGQLFDYIQSIT 457

  Fly   504 GLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVVAQIVS--------VEQPALPTSI 560
            ..:......:|.|.|.||:.|..|||||    |.:.:.||:...|..        |.....||.|
Zfish   458 SYLAPPIAAVFALAIFCKRVNEPGAFYG----LCVGLLVGLARMITEFAYGTGSCVNPSNCPTII 518

  Fly   561 DKCDCH----------VNMTNIIG-SLLTEPLE 582
              |..|          ::...|:. ||:|:|:|
Zfish   519 --CGVHYLYFALILFGLSCILILSISLMTKPIE 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	138/553 (25%)
slc5a1	NP_956975.1	SLC5sbd_SGLT1	27..658	CDD:271379	138/553 (25%)