Protein Alignment CG5687 and slc5a12

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_956662.1
• Gene: slc5a12 / 393339
• ZFINID: ZDB-GENE-040426-1343
• Length: 623
• Species: Danio rerio
• Alignment Length: 616
• Identity: 197/616 - (31%)
• Similarity: 339/616 - (55%)
• Gaps: 57/616 - (9%)

  Fly    96 FSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGS-EMSIFPVTLSLTTSFITAIELLGN 159
            |...|||:...:.|:|.|||:|:...::..:.|.|||:|. :||..||.||||.||::|:.::|.
Zfish     7 FQAGDYVVFACLFVVSSGIGVFFAIKERNKAPSKEFLVGGRQMSCGPVALSLTASFMSAVTVIGA 71

  Fly   160 PSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKEIRILGAVLYVIQM 224
            |:::|..|..:|:..:....|:....::|.|::::..:||.||||.:||.|.:|:...::|:||.
Zfish    72 PADVYRFGASYVIFGVAYTFVVFFTAELFLPVFYRSGITSTYEYLELRFCKLVRVAATLIYIIQT 136

  Fly   225 CFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVLIV 289
            ..||.|.|.|||:||::.||.|...::....:||.||.:.||:||||..|:||..|:.|..:.::
Zfish   137 ILYTGVVVYAPALALNQVTGFDLWGSIFATGIVCTFYCTLGGLKAVVWTDAFQMVVMVVGFLTVL 201

  Fly   290 GLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVIGGFFYWTSLFCTNQASVQKCMS 354
            ..|...:|....|:.|:....||:.|:.|..|..|||.|::.:||.|.|..::..||:::|:|:|
Zfish   202 IQGSSRAGGIENVWSTSRTGGRLQVFDFDVSPLRRHTFWTLSVGGTFTWLGIYGVNQSTIQRCIS 266

  Fly   355 LKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVINTYEHI 419
            .|:...|:.||...::||.::......:||:::::|:.|||.::|.|||.|||:||:|:......
Zfish   267 CKTEGHARWALYLNLLGLWIILFCAVVSGLIMYSYYSHCDPWSSGLISAPDQLMPYFVMEILGAF 331

  Fly   420 SSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKGATYAKWMS----LGFGI 480
            ..:.|:|||..|:.:|.|||:::|:|:.|..||.:     .:..|:.....|.|:|    :.||:
Zfish   332 PGLPGLFVACAFSGTLSTVAASINALATVMYEDFV-----SQCFPDLSNRAASWISKALCVAFGV 391

  Fly   481 ASFGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVV 545
            |...:.....::||::||.|:::|:.||..||||.|||.....|.|||..|.::.::|..:|||.
Zfish   392 ACTTMAVAASYMGGIVQAALSIHGMCGGPVLGLFSLGILFPFTNLKGAVGGLIVGISLSFWVGVG 456

  Fly   546 AQIVSVEQPALPTS------IDKCDCHVNM-----TNIIGSLLTEPLEVIEEGGFTSWPIFRLSY 599
            |.|    .|| |::      ::...|::..     |:...:.||.....:.:    ||  :.:||
Zfish   457 AFI----YPA-PSNNTHALELNTAGCNITAAAFEPTSATVTQLTSDRNWLAD----SW--YSMSY 510

  Fly   600 MWYSMIGCLLTVFLGWFISLIIDFIQRRNVLKITGKDIDNPAVSEEIFKSDSQV-----QYTTTT 659
            ::||.:|.:.||..|..|:|            :|| .:|...:...:.:|..:|     :..|..
Zfish   511 LYYSAVGFIGTVAAGLLITL------------LTG-PMDPKLLKPGMTRSVKEVMCFCTEKFTEA 562

  Fly   660 VIGDPRELTSD-----EGHVNH--AIRIDDE 683
            .:|:.:|...|     |.|.:.  .:|:|::
Zfish   563 DLGEGKEDVGDFGKAWEKHPDQGCTLRMDEK 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	182/536 (34%)
slc5a12	NP_956662.1	SLC5sbd_SMCT2	4..533	CDD:212089	184/553 (33%)