DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5687 and RGD1563815

DIOPT Version :9

Sequence 1:	NP_001286910.1	Gene:	CG5687 / 38255	FlyBaseID:	FBgn0035293	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	XP_006256382.1	Gene:	RGD1563815 / 365549	RGDID:	1563815	Length:	695	Species:	Rattus norvegicus

Alignment Length:	558	Identity:	126/558 - (22%)
Similarity:	227/558 - (40%)	Gaps:	104/558 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 SGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSEMSIFPVTLSLTTSFITAIELLGNPS 161
            |..|.:::...|::.|.||::.......|:..:.||.|..::.:.:.||:.:|.:.:...:|...
  Rat    23 STVDTLVMTFYLLLVLCIGLWALLSHSRGTIKDFFLAGQNLAWWLMGLSIYSSTVGSGHFMGLAG 87

  Fly   162 EMYFQG---------TQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKEIRI--- 214
            .....|         |.|:|.::..         ||.|||.|..:.:..|||..||| .:||
  Rat    88 IGAASGIAVGAFEWNTVFMLFMLGW---------IFVPIYSKAGVVTLPEYLKKRFG-SVRIQLF 142

  Fly   215 LGAVLYVIQMCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAA 279
            ...|..::.:....::.:...|:.|.....:|....::.:..:...|:..||:..|...::.||.
  Rat   143 FSFVFLIVYILSRISMEIGFGAMFLKMVWDIDIYQTMLTVLTITGVYTITGGLATVAYVETLQAG 207

  Fly   280 VLAVSLVLIVGLGCFYSGNPIQVFQTASD--HNRLEFFNMDPDP---TTRHTVWSV---VIGGFF 336
            ::.:...|::|...:..|...::....|.  .:.::..|....|   |.|...:.|   .:.|..
  Rat   208 IMVLGSALLMGYAFYEVGGYQELVNKYSKAIPSTIQQGNWTAKPECYTPREDAFHVFRSCVSGDV 272

  Fly   337 YW---------TSLF--CTNQASVQKCMSLKS-LRLAKIALGFAIIGLIVVFLLNFYTGLMVFTH 389
            .|         .|||  |.:|.|||:.::.|| |.:....|....:.|:.:||: ...|::....
  Rat   273 PWPGLVLGATTVSLFYGCADQVSVQRFLAGKSRLHMEGGCLLCGYLKLLPMFLM-VMPGMISRVL 336

  Fly   390 YAD---------CDPLTAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTV-ASALNS 444
            :.|         |:.. .||.:.. ..|.|.|:        |.|:..:|:....|.|| ||.::|
  Rat   337 FPDQVACVVPSECEKF-CGRGTGC-SALAYPVL--------VLGVMPSGLQGFMLSTVCASLMSS 391

  Fly   445 LSAVTCEDLLVNGMNIKISPEKGATYAKWMSLG-FGIASFGLVFIV--------------EHLGG 494
            |:::......:..:||.......||..:.|..| |.:.....|.||              |:: .
  Rat   392 LTSIFNSSSALFTLNIYTWIRPTATEKELMIAGRFFVIILLAVTIVWIPIIEMAPSETLFEYM-Q 455

  Fly   495 VLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVVAQI-----VSVEQP 554
            :|::.||     ..|| .:|:|.:.||:.|.:|||:|.:|...:.:| .::|:.     ...|..
  Rat   456 ILKSCLT-----PSVT-AVFLLAVFCKRVNEQGAFWGLILGSTIGVF-RLLAEFFYGPPTCGEDR 513

  Fly   555 ALPTSIDKCDCH----------VNMTNIIG-SLLTEPL 581
            ..|..|  |..|          |::..|:. ||.|||:
  Rat   514 QCPIFI--CGLHYLYFGFCLLLVSILIILAISLATEPI 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	125/556 (22%)
RGD1563815	XP_006256382.1	SLC5-6-like_sbd	26..695	CDD:294310	125/555 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810