Protein Alignment CG5687 and Slc5a12

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_001102058.1
• Gene: Slc5a12 / 362188
• RGDID: 1311652
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 199/556 - (35%)
• Similarity: 321/556 - (57%)
• Gaps: 37/556 - (6%)

  Fly    95 TFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGS-EMSIFPVTLSLTTSFITAIELLG 158
            :|..:|||:...:.|||.|||:|:...::..::|.|||:|. :||..||.||||.||::|:.:||
  Rat     5 SFEAWDYVVFAALFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFAPVALSLTASFMSAVTVLG 69

  Fly   159 NPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKEIRILGAVLYVIQ 223
            .|:|:|..|..|::.:|....|:....::|.|::::..:||.||||.:||.|.:|....::|::|
  Rat    70 TPAEVYRFGASFLIFLISYAFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYILQ 134

  Fly   224 MCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVLI 288
            ...||.|.|.|||:||::.||.:...:|....:||.||.|.||:||||..|:||..|:.|..:.:
  Rat   135 TILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTV 199

  Fly   289 VGLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVIGGFFYWTSLFCTNQASVQKCM 353
            :..|..:.|....|.:.|.:.:||:..:.|.||..|||.|::.:||.|.|..::..||:::|:|:
  Rat   200 LIQGSNHVGGFDNVLEQARNGSRLDIVDFDVDPLRRHTFWTIAVGGTFTWLGIYGVNQSTIQRCI 264

  Fly   354 SLKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVINTYEH 418
            |.|:.:.||:||.|.::||.::.:...:.||:::.:|.||||.|:|.|.|.|||:||:|:..:..
  Rat   265 SCKTEKHAKLALYFNLLGLWIIVVCAVFCGLIMYAYYKDCDPWTSGAILAPDQLMPYFVMEIFAT 329

  Fly   419 ISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKGATYAKWMSLG----FG 479
            :..:.|:|||..|:.:|.|||:::|:|:.||.||.:.:     ..|....|.:.|:|.|    ||
  Rat   330 MPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKS-----CFPHLSDTLSTWISKGLCLLFG 389

  Fly   480 IASFGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVGV 544
            |....:..:...:|.|:||.|:::|:.||..||||.||:.....|.|||..|.|..:.|..:||:
  Rat   390 IICTSMAVLASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTGITLSFWVGI 454

  Fly   545 VAQIVSVEQPA-------LPTSIDKCDCHVNMTNIIGSLLTEPLEVIEEGGFTSWPIFRLSYMWY 602
            .|.:    .||       ||.|.:.|......|.....|.:.|  |:.:    :|  :.|||:::
  Rat   455 GAFV----YPAPDSKTLPLPLSTEFCVQQNKTTTEAYQLSSRP--VLAD----TW--YSLSYLYF 507

  Fly   603 SMIGCLLTVFLGWFISLIIDFIQRRNVLKITGKDID 638
            |.:|||..:..|    :||.|:..|.    .|||:|
  Rat   508 SAVGCLGCIAAG----IIISFLTGRQ----RGKDVD 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	190/532 (36%)
Slc5a12	NP_001102058.1	SLC5sbd_SMCT2	3..527	CDD:212089	194/542 (36%)