DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5687 and CG31668

DIOPT Version :9

Sequence 1:	NP_001286910.1	Gene:	CG5687 / 38255	FlyBaseID:	FBgn0035293	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_001097055.2	Gene:	CG31668 / 33395	FlyBaseID:	FBgn0051668	Length:	590	Species:	Drosophila melanogaster

Alignment Length:	574	Identity:	187/574 - (32%)
Similarity:	307/574 - (53%)	Gaps:	42/574 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 FSGYDYVILLGMLVISLGIGIFYGFFQK----------------------GGSSSNEFLLGS-EM 137
            |...||.:.||:.::|:.||:::||.:|                      |....|::::|| .:
  Fly     6 FGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNL 70

  Fly   138 SIFPVTLSLTTSFITAIELLGNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYE 202
            .:|||.:||..|.|:|:.::|.|||:|..|||:..|||.:|:.......|:.|::..:::||.||
  Fly    71 RVFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQVTSSYE 135

  Fly   203 YLGIRFGKEIRILGAVLYVIQMCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGM 267
            ||.:||...||.:.::::::.:..|.......||:||::.:|::..:....|.|:||.|:..||:
  Fly   136 YLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGL 200

  Fly   268 KAVVIADSFQAAVLAVSLVLIVGLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVI 332
            ||||..|.:|..::..|::.||.|...|..:.....:......||.|...:|.|..|||||||||
  Fly   201 KAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLVRGGRLIFSETNPSPFARHTVWSVVI 265

  Fly   333 GGFFYWTSLFCTNQASVQKCMSLKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLT 397
            |..||||||...:|..|.:.|||.:|::|:.::.|.::|......|..|.||::|..|.|||||:
  Fly   266 GNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAYRDCDPLS 330

  Fly   398 AGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKI 462
            ||.|...|||:|.:|:|:..|:..:.|:|:||||.|||.:::..|||.|.|..:||:.....:::
  Fly   331 AGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKMEL 395

  Fly   463 SPEKGATYAKWMSLGFGIASFGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKG 527
            .........|...:..|:.:|.:||::|.:.|||..:::|..:....|.|:|.:|:....|||.|
  Fly   396 GEWASTIVVKGSIVVLGLLAFAMVFVLEKVSGVLSISVSLAAIAASSTFGIFTVGMLVPWANTVG 460

  Fly   528 AFYGGLLSLALVIFVGVVAQIVSVE----QPALPTSIDKCDCHVNMTNIIGSLLTEPLEVIEEGG 588
            ...||:.|:.|..::...:|..:..    ...||.|::.|        :..:.:.|...|.||..
  Fly   461 TAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGC--------LANASVAENAWVAEEEV 517

  Fly   589 FTSWPIFRLSYMWYSMIGCLLTVFLGWFISLIIDFIQRRNVLKITGKDIDNPAV 642
            |   |::||||.|.|.||.|..|.:|..:||    :.:...:|....|:..|.:
  Fly   518 F---PLYRLSYHWISPIGVLTVVVVGSLVSL----VTKPTDIKSLDSDLITPVI 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	182/547 (33%)
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	176/532 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	233	1.000	Domainoid score	I1353
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1946
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D32058at33392
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	9	8.970