DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5687 and CG32669

DIOPT Version :9

Sequence 1:	NP_001286910.1	Gene:	CG5687 / 38255	FlyBaseID:	FBgn0035293	Length:	683	Species:	Drosophila melanogaster
Sequence 2:	NP_727460.1	Gene:	CG32669 / 326229	FlyBaseID:	FBgn0052669	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	562	Identity:	200/562 - (35%)
Similarity:	333/562 - (59%)	Gaps:	18/562 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 ATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGS-EMSIFPVTLSLTTSFITAIELL 157
            ||...:||.||..:|:||:.|||:|.|.....|::.|:||.. .|::.||..||..||::|:.:|
  Fly     2 ATLGAWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTIL 66

  Fly   158 GNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKEIRILGAVLYVI 222
            |...|.|..||.||:|.:..|:..|||..:..|::::::..|.||||.:|||...|:..::.:.:
  Fly    67 GVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSL 131

  Fly   223 QMCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVL 287
            ||..|..:.|.|||:||...|||....::|::.|||.||::.||||||:|.|.:|:.::..::..
  Fly   132 QMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFS 196

  Fly   288 IVGLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVIGGFFYWTSLFCTNQASVQKC 352
            ::......:|:...:::.|.::.|:...|...|||.|||.::.::||...:.:::..||..||:.
  Fly   197 VIICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRL 261

  Fly   353 MSLKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVINTYE 417
            |::|||..|:.||.:.:..|.::.|...::||.::.:|.|||||..||:::.||::|.:|::|..
  Fly   262 MAVKSLSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTMG 326

  Fly   418 HISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNI----KISPEKGATYAKWMSLGF 478
            ..:.:||:||:|||.|||.|::|.::||:|||.||.|...::.    .::..:...|:|.:||.|
  Fly   327 EYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFF 391

  Fly   479 GIASFGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVG 543
            |....|:.|:...:||:|||.|::.|:|||..||||.||:...:||.|||..|.|:|||...::|
  Fly   392 GALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCFWIG 456

  Fly   544 VVAQIVSVEQPALP-TSID--KCDCHVNMTNIIGSLLTEPLEVIEEGGFTSWPIFRLSYMWYSMI 605
                   ..||..| .|:|  ...|.|:.:......|...:.|.||..:  :.::|:|||||:.:
  Fly   457 -------FGQPKPPLVSLDMSTAGCPVDRSFARDIFLKTVIAVAEEEHY--FYLYRISYMWYAAL 512

  Fly   606 GCLLTVFLGWFISLIIDFIQRRNVLKITGKDIDNPAVSEEIF 647
            |.|:|.|.||.:|.:...::..|..:|. :|.|...:..::|
  Fly   513 GFLITFFGGWLLSWLFALLKWDNNRRIY-QDADCTLIKHDLF 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	193/528 (37%)
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	193/528 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	233	1.000	Domainoid score	I1353
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1946
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	9	8.970