Protein Alignment CG5687 and Slc5a4b

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: XP_008771154.1
• Gene: Slc5a4b / 294342
• RGDID: 1309867
• Length: 660
• Species: Rattus norvegicus
• Alignment Length: 620
• Identity: 143/620 - (23%)
• Similarity: 257/620 - (41%)
• Gaps: 134/620 - (21%)

  Fly    49 RGESPSESQEHVEFDNAATLLLRAFKNQQIPASAELEECSAPSHKATFSGYDYVILLGMLVISLG 113
            |.|.|.|..|.::  |||.:                                .||::..||: |.
  Rat    12 RTEEPPEVSERIQ--NAADI--------------------------------SVIVIYFLVV-LA 41

  Fly   114 IGIFYGFFQKGGSSSNEFLLGSEMSIFPVTLSLTTSFITAIELLGNPSEMYFQGTQFVLIVIPMV 178
            :|::.......|:....||.|.::|.:|:..||..|.|.:...:|........|.....:....:
  Rat    42 VGLWSMVRSNRGTIGGFFLAGRDVSWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVEWNAL 106

  Fly   179 IVIPVAVKIFYPIYFKMELTSCYEYLGIRF-GKEIRILGAVLYV-IQMCFYTAVAVLAPAIALSK 241
            :::.|...:|.|||.|..:|:..|||..|| ||.::|..:||.: |.:...|:..:.:.||.:..
  Rat   107 LMVLVLGWVFVPIYIKAGVTTMPEYLRKRFGGKRLQIYLSVLSLFIMVAIQTSSTIFSGAIFIQL 171

  Fly   242 ATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVLIVG-----LGCF--YSGNP 299
            |.||:..:||.::..:..||:..||:.:|:..||.|..::.|..::::|     :|.:  ::...
  Rat   172 ALGLNLYLAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLVGSLILMGFAFAEVGGYESFTEKY 236

  Fly   300 IQVFQTASDHNRL-----------EFFNMDPDPTTRHTVWSVVIGG-----FFYWTSLFCTNQAS 348
            :....:..:.:.|           :.|::..||......|..:|.|     .:||    |.:|..
  Rat   237 MNAIPSVVEGDNLTISPKCYTPQPDSFHIFRDPINGDIPWPGLIFGMTILAIWYW----CADQVM 297

  Fly   349 VQKCM---SLKSLRLAKIALGFAIIGLIVVFLL--------NFYTGLMVFTHYADCDPLTAGRIS 402
            ||:|:   ::..::.|.|..|:  :.|:.:||:        ..||..:.....::|.......:.
  Rat   298 VQRCLCGKNMSHVKAACIMCGY--LKLLPMFLMVMPGMISRILYTDKVACVVPSECVKQCGTAVG 360

  Fly   403 ATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKG 467
            .|:...|..|:....  ..:.|:.::.:.|:.:.::.|..||.|.:...||..     ||  .|.
  Rat   361 CTNYAYPTLVLELMP--DGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDLYT-----KI--RKK 416

  Fly   468 ATYAKWMSLGFGIASFGLVFIVEHL-----------GGVLQATLTLNGLIGGVTLGLFVLGIACK 521
            |:..:.|..|   ..||:|.||..:           |.:.....:.:..||.....:|:|.|.||
  Rat   417 ASERELMVAG---RVFGIVLIVISILWVPLIQASQNGQLFHYISSFSSYIGPPVGAVFLLAIFCK 478

  Fly   522 QANTKGAFYGGLLSLALVIFVGVVAQIVS--------VEQPALPTSIDKCDCH----------VN 568
            :.|.:|||:|  |.:.|||  |::..|..        :|....|..|  |..|          |:
  Rat   479 RVNEQGAFWG--LMVGLVI--GLIRMITEFIYGTGSCLEPSNCPRII--CGVHYMYFAIILFFVS 537

  Fly   569 MTNIIG-SLLTEPLEVIEEGGFTSWPIFRLSY-MW 601
            :..|:| |.||||:..:.        ::||.: :|
  Rat   538 ILVILGVSFLTEPIPDVH--------LYRLCWSLW 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	135/570 (24%)
Slc5a4b	XP_008771154.1	SLC5-6-like_sbd	27..660	CDD:444915	136/603 (23%)