Protein Alignment CG5687 and Slc5a11

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_666310.1
• Gene: Slc5a11 / 233836
• MGIID: 1919316
• Length: 673
• Species: Mus musculus
• Alignment Length: 675
• Identity: 155/675 - (22%)
• Similarity: 268/675 - (39%)
• Gaps: 157/675 - (23%)

  Fly    77 QIPASAELEECSAPSHKATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSEMSIFP 141
            |.|.|..||.....|.:..    |..:|:...:..|.:|::.....|..:....||.|.:|..:|
Mouse     9 QPPQSDSLEAFPQKSMEPA----DIAVLVLYFLFVLAVGLWSTVRTKRDTVKGYFLAGGDMVWWP 69

  Fly   142 VTLSLTTSFITAIELLGNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGI 206
            |..||..|.:.:...:|........|.......:..:..:.:...:|.|||...::|:..|||..
Mouse    70 VGASLFASNVGSGHFIGLAGSGAAVGISVAAYELNGLFSVLMLAWVFLPIYIAGQVTTMPEYLRR 134

  Fly   207 RF-GKEIRILGAVLYVIQMCFYTAVAV--LAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMK 268
            || |..|.|..||||:. :..:|.::|  .|.||.:.::..||..:|:|.:..:...|:..||:.
Mouse   135 RFGGNRISITLAVLYLF-IYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITALYTVAGGLA 198

  Fly   269 AVVIADSFQAAVLAVSLVLIVGLGCFYS--------GNPIQVFQTASDHN---------RLEFFN 316
            ||:..|:.|..::.:...:::|    ||        |...|.|...:.:.         |.:.|:
Mouse   199 AVIYTDALQTVIMLIGAFILMG----YSFAAVGGMEGLKDQYFLALASNRSENSSCGLPREDAFH 259

  Fly   317 MDPDPTTRHTVWSVVIGG-----FFYWTSLFCTNQASVQKCMSLKSLRLAK-IALGFAIIGLIVV 375
            :..||.|....|..::.|     .:||    ||:|..||:.::.|:|..|| .:|..|.:.::.:
Mouse   260 IFRDPLTSDLPWPGILFGMSIPSLWYW----CTDQVIVQRSLAAKNLSHAKGGSLMAAYLKVLPL 320

  Fly   376 FLLNF--------YTGLMVFTHYADCDPLTAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFA 432
            ||:.|        :...:...|...|..:.:.....:|...|..|:....  :.:.|:.:|.:.|
Mouse   321 FLMVFPGMVSRVLFPDQVACAHPDICQRVCSNPSGCSDIAYPKLVLELLP--TGLRGLMMAVMVA 383

  Fly   433 ASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKGATYAKWMSLGFGIASFGLVFI--------- 488
            |.:.::.|..||.|.:...||..:     |.|.  |:..:.|.:| .|..|.||.:
Mouse   384 ALMSSLTSIFNSASTIFTMDLWNH-----IRPR--ASERELMIVG-RIFVFALVLVSILWIPIVQ 440

  Fly   489 ----------VEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVG 543
                      ::.:...||..:.:          :|::|...|:.|.||||.|.:|.|.|    |
Mouse   441 ASQGGQLFIYIQSISSYLQPPVAM----------VFIMGCFWKRTNEKGAFSGLILGLLL----G 491

  Fly   544 VVAQIVS--VEQPALPTSIDKCDCHVNMTNIIGSLLTEPLE---VIEEGGFTSWPIFRLSYMWYS 603
            :|..|:.  ..||       :||              :|.:   |:::          :.|:::|
Mouse   492 LVRLILDFVYAQP-------RCD--------------QPDDRPAVVKD----------VHYLYFS 525

  Fly   604 MI---GCLLTVF-LGWF--------ISLIIDFIQRRNVLKITGKDIDNPAVSEEIFKSDS----- 651
            ||   ..|:||. :.||        :|.:..|.:...|.:   ||...|.....:..|.:
Mouse   526 MILSFTTLITVVTVSWFTETPSKEMVSRLTWFTRHEPVAQ---KDSAPPETPLSLTLSQNGTTEA 587

  Fly   652 --------QVQYTTTTVIGD---PR 665
                    .||.:||...||   ||
Mouse   588 PGTSIQLETVQESTTKACGDGVSPR 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	135/590 (23%)
Slc5a11	NP_666310.1	SLC5-6-like_sbd	28..673	CDD:444915	149/652 (23%)