Protein Alignment CG5687 and slc-5A12

DIOPT Version :10

• Sequence 1: NP_647678.3
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_001041067.1
• Gene: slc-5A12 / 178127
• WormBaseID: WBGene00014092
• Length: 577
• Species: Caenorhabditis elegans
• Alignment Length: 567
• Identity: 151/567 - (26%)
• Similarity: 282/567 - (49%)
• Gaps: 30/567 - (5%)

  Fly   100 DYVILLGMLVISLGIGIFYG-----FFQKGG-SSSNEFLLGS-EMSIFPVTLSLTTSFITAIELL 157
            ||.|....:.:||..|:::.     ..::|. ::..|:|:|. ::...||.|||.|:|::.|.:|
 Worm    11 DYAIFGLSIGLSLSTGVYHAIKSRIILRRGDRTAKEEYLMGGRQLPPLPVALSLLTTFLSGILML 75

  Fly   158 GNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGK-EIRILGAVLYV 221
            |.|:||:.:|.|..|..:..|....|...:|.|::.||:.|..:||...|:.. .||.|.::|::
 Worm    76 GVPAEMFQRGAQIWLNFVIGVASSIVTCFVFLPVFHKMKSTCLHEYFIHRYNSILIRRLFSLLFL 140

  Fly   222 IQMCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLV 286
            :....|.:|.:.||::|||....::....|::.......|:..||:||||..||.||.::...:.
 Worm   141 LFTIVYMSVVLYAPSVALSPVLQINKWYLVLIFGCTTTLYTCLGGLKAVVWTDSLQAVIMYTGVF 205

  Fly   287 LIV--GLGCFYSGNPIQVFQTASDHNRL-EFFNMDPDPTTRHTVWSVVIGGFFYWTSLFCTNQAS 348
            .::  ||.....|...:|...|.|..|: |...||......:::|..:..|...|.:.|..||.:
 Worm   206 TLIYKGLSHPRVGGLERVLSIAWDSGRISELGRMDWRIDQYNSLWINLFSGTIVWLASFGVNQLA 270

  Fly   349 VQKCMSLKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVI 413
            :|:..||.||::|:..:.:.:....|:..:..:.|.:...::.:|:||..|.:..:|.:...:..
 Worm   271 IQRYASLPSLKVAQSIIIYTLAPFTVLCSIVAFVGFIALAYFYNCNPLETGEVKESDHITISFAR 335

  Fly   414 NTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKGAT-YAKWMSLG 477
            :..:....:.|::|:.|.:|:|.|::|.:||::|...||.|.|.::.||: :.||| ..|.:.|.
 Worm   336 DILQPTPGLFGLYVSCIMSATLSTLSSGMNSMAAAIYEDFLKNSLDGKIT-DTGATRLNKIIVLI 399

  Fly   478 FGIASFGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFV 542
            .|::|.||.|:.|.|||.|:..:::.|.:.|..:.:|||.:...::.:|.......||....:.:
 Worm   400 CGLSSTGLAFLAEVLGGSLRICISVMGAMSGPMVAIFVLALFFPKSGSKSCLISFFLSNLFCLII 464

  Fly   543 GVVAQIVSVEQP----ALP--TSIDKCDCHVNMTNIIGSLLTEPLEVIEEGGFTSWPIFRLSYMW 601
            .:...|   :.|    .||  |:::.|:.:.|.|     :...|......|...:..|.|:|...
 Worm   465 CIANYI---QDPYHDLFLPTNTTLEGCNGNSNFT-----IRMMPTYDAHYGNPDTLYISRISTYS 521

  Fly   602 YSMIGCLLTVFLGWFISLIIDF---IQRRNVLKITGKDIDNPAVSEE 645
            |:.:|.:|.:.:||..||..:.   :::...|..:|::...|....|
 Worm   522 YAGVGFVLMIIIGWIASLFEESDHKVEKIRHLTFSGRNEPWPDTHHE 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_647678.3	SLC5sbd_NIS-SMVT	99..620	CDD:271383	146/537 (27%)
slc-5A12	NP_001041067.1	SLC5sbd_NIS-SMVT	11..540	CDD:271383	146/537 (27%)