Protein Alignment CG5687 and SLC5A8

DIOPT Version :9

• Sequence 1: NP_001286910.1
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_666018.3
• Gene: SLC5A8 / 160728
• HGNCID: 19119
• Length: 610
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 211/611 - (34%)
• Similarity: 333/611 - (54%)
• Gaps: 64/611 - (10%)

  Fly    90 PSHKATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGS-EMSIFPVTLSLTTSFITA 153
            |....||..:|||:..||||||..|||:|.|...|..:|.:||:|. .|:..||.||||.||::|
Human     4 PRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSA 68

  Fly   154 IELLGNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRFGKEIRILGAV 218
            :.:||.|||:|..|..|.:.......|:.::.::|.|:::|:.:||.||||.:||.|.:|:.|.|
Human    69 VTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKCVRLCGTV 133

  Fly   219 LYVIQMCFYTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAV 283
            |:::|...||.:.:.|||:||::.||.|...|||...|||.||.:.||:|||:..|.||..::..
Human   134 LFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVFQVGIMVA 198

  Fly   284 SLVLIVGLGCFYSGNPIQVFQTASDHNRLEFFNMDPDPTTRHTVWSVVIGGFFYWTSLFCTNQAS 348
            ....::.......|....:...|.|..||.|:|.:|:|..|||.|:::|||.|.|||::..||:.
Human   199 GFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTIIIGGTFTWTSIYGVNQSQ 263

  Fly   349 VQKCMSLKSLRLAKIALGFAIIGLIVVFLLNFYTGLMVFTHYADCDPLTAGRISATDQLLPYYVI 413
            ||:.:|.||...||::|...::||..:...:.:.||.:::.|.||||.||.::||.|||:||.|:
Human   264 VQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYHDCDPWTAKKVSAPDQLMPYLVL 328

  Fly   414 NTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKGATYAKWMSLGF 478
            :..:....:.|:|||..::.:|.||:|::|:|:|||.|||:..... .:|....:..::.||:.:
Human   329 DILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFR-SLSERSLSWISQGMSVVY 392

  Fly   479 GIASFGLVFIVEHLGGVLQATLTLNGLIGGVTLGLFVLGIACKQANTKGAFYGGLLSLALVIFVG 543
            |....|:..:...:|.:|||.|::.|::||..:|||.|||....||:.||..|.:...|:.::||
Human   393 GALCIGMAALASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISLWVG 457

  Fly   544 VVAQIVSVEQPALP-------TSIDKCDCHVNMTNI--------------IGSLLTEPLEVIEEG 587
            :.|||    .|.||       ..|..|:...|.||:              |.::...||
Human   458 IGAQI----YPPLPERTLPLHLDIQGCNSTYNETNLMTTTEMPFTTSVFQIYNVQRTPL------ 512

  Fly   588 GFTSWPIFRLSYMWYSMIGCLLTVFLGWFISLII----------------DFI-------QRRNV 629
             ..:|  :.|||:::|.:|.|:|:.:|..:||..                ||:       ::::|
Human   513 -MDNW--YSLSYLYFSTVGTLVTLLVGILVSLSTGGRKQNLDPRYILTKEDFLSNFDIFKKKKHV 574

  Fly   630 LKITGKDI-----DNPAVSEEIFKSD 650
            |......:     ||||.:.....||
Human   575 LSYKSHPVEDGGTDNPAFNHIELNSD 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	197/542 (36%)
SLC5A8	NP_666018.3	SLC5sbd_SMCT1	7..549	CDD:271402	200/555 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..610		6/16 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.920