Protein Alignment CG5687 and SLC5A10

DIOPT Version :9

• Sequence 1: NP_001286910.1
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 129/611 - (21%)
• Similarity: 230/611 - (37%)
• Gaps: 142/611 - (23%)

  Fly   100 DYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSEMSIFPVTLSLTTS------FI--TAIEL 156
            |.:::.....:::.:||:........:.:..||.|.:|:.:|:..||..|      ||  .....
Human    20 DIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGA 84

  Fly   157 LGNPSEMYFQ-GTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRF-GKEIRILGAVL 219
            .|..:...|: ...:||:.:..|         |.|||...|:.:..||:..|: |:.||:..:||
Human    85 AGGLAVAGFEWNATYVLLALAWV---------FVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVL 140

  Fly   220 YVIQMCFYTAVA--VLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLA 282
            .:: :..:|.::  :.|.|:.:....|.:..::.:|...:...|:..||:.||:..|:.|..::.
Human   141 SLL-LSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMV 204

  Fly   283 VSLVLIV--------GLG----CFYSGNPIQVFQTASDH-NRLEFFNMDPDPTTRHTVWS----- 329
            |..|::.        |.|    .:....|.:.....:.| .|.:..:|..||.|....|:
Human   205 VGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFG 269

  Fly   330 VVIGGFFYWTSLFCTNQASVQKCMSLKSLRLAKIA------LGFAIIGLIV---VFLLNFYTGLM 385
            :.|...:||    ||:|..||:.:|.:.|..||..      |....:|||:   :.....:.|..
Human   270 LTIMATWYW----CTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPGAH 330

  Fly   386 VFTHY----------------ADCDPLTAGRISATDQLLPYYVINTYEHISSVAGIFVAGIFAAS 434
            |:...                ::|.......:..::...|..|:....  ..:.|:.:|.:.||.
Human   331 VYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMP--IGLRGLMIAVMLAAL 393

  Fly   435 LGTVASALNSLSAVTCED--------------LLVNGMNIKISPEKGATYAKWMSLGF------- 478
            :.::.|..||.|.:...|              |||....|..:|.     |....|.|
Human   394 MSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRTGIPSTPP-----APQSRLSFLLPETPP 453

  Fly   479 ------GIASFGLVFIVEHLGGVLQATLTL-----------------NGLIGGVTLGLFVLGIAC 520
                  |:....|..::..|.||..|.:.:                 :.|...|| .:||||:..
Human   454 LERYLLGLVVMDLWLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVT-AVFVLGVFW 517

  Fly   521 KQANTKGAFYGGLLSLALVIFVGVVAQIVSVEQPALPT-----------SIDKCDCHVNM----- 569
            ::||.:|||:|.:..|.    ||....::....||.|.           ||......|.:
Human   518 RRANEQGAFWGLIAGLV----VGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSG 578

  Fly   570 -TNIIGSLLTEPLEVIEEGGFTSWPI 594
             ..:.|||||.|.:.::....|.|.:
Human   579 AVVVAGSLLTPPPQSVQIENLTWWTL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	129/611 (21%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:320982	129/611 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810