Protein Alignment Dbx and BARX2

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_003649.2
• Gene: BARX2 / 8538
• HGNCID: 956
• Length: 279
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 76/255 - (29%)
• Similarity: 106/255 - (41%)
• Gaps: 62/255 - (24%)

  Fly   370 PPVIAKPMP---------SRPTPFL------PHTLNH-----PHLHSLLAHCRNPYMSVGAQVFP 414
            |.::.:|.|         .|..|.|      |..::|     |.:...|: |.....:|.|:.
Human    49 PSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPATPGIAQALS-CHQVTEAVSAEA-- 110

  Fly   415 LPPGQGFPWAHS-------TRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLG 472
             |.|:....:.|       .:.||||.   |.:|::.|..||||:||:|||:|.|||..||:.||
Human   111 -PGGEALASSESETEQPTPRQKKPRRS---RTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLG 171

  Fly   473 LKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLPN---KNNPNPDLSDAKCDRPLT------ 528
            |...|||.|:|||||||     ::::..||....|.|.   |.|..|...:.:.:..:.
Human   172 LTQLQVKTWYQNRRMKW-----KKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQ 231

  Fly   529 -PLSPSLLSPNGSATPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPL 587
             .|.||...........|.   |:|.|...|..|..||.:...|          |.||||
Human   232 EQLEPSQGQEELCEAQEPK---ARDVPLEMAEPPDPPQELPIPS----------SEPPPL 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	32/53 (60%)
BARX2	NP_003649.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..137		7/32 (22%)
		Homeodomain	134..190	CDD:459649	34/63 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..279		24/98 (24%)