Protein Alignment Dbx and Lbx1

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001040573.1
• Gene: Lbx1 / 499362
• RGDID: 1564197
• Length: 285
• Species: Rattus norvegicus
• Alignment Length: 290
• Identity: 77/290 - (26%)
• Similarity: 104/290 - (35%)
• Gaps: 101/290 - (34%)

  Fly   368 PPPPVIAKPMPSRPTPF-LPHTLNHPHLHSLLAHCRNPYMSVGAQVFPLPPGQGFPWA------- 424
            |||....||:    ||| :...||.|.:....:.|...::...|...  .|| |.|.|
  Rat    24 PPPANSNKPL----TPFSIEDILNKPSVRRSYSLCGAAHLLAAADKH--APG-GLPLAGRALLSQ 81

  Fly   425 ----------------------------------HSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQ 455
                                              ...|..|::....|..|::.|...|||||..
  Rat    82 TSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLY 146

  Fly   456 QKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSD 520
            |||:|..||.::|::|||.::||..||||||.|.:...| |:.|                 |:..
  Rat   147 QKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLE-EMKA-----------------DVES 193

  Fly   521 AKCDRPLTPLSPS---------LLSPNGSATPPPPG------AVAKDEPPTAAVTPKSPQSVSSR 570
            ||      .|.||         .|..|..|:....|      ..||..|.:.|:.|.:||:..
  Rat   194 AK------KLGPSGQMDIVALAELEQNSEASGGGGGGGGGGCGRAKSRPGSPALPPGAPQAPG-- 250

  Fly   571 SSPSVGYGLQISSPPPLLTSLKMGDQSASA 600
                 |..||:|...||.      ||.||:
  Rat   251 -----GGPLQLSPASPLT------DQRASS 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	27/53 (51%)
Lbx1	NP_001040573.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		6/15 (40%)
		Homeodomain	126..182	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..285		20/71 (28%)