Protein Alignment Dbx and E5

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 647
• Identity: 147/647 - (22%)
• Similarity: 207/647 - (31%)
• Gaps: 226/647 - (34%)

  Fly   129 VEPKETSMPTVGNTILKDTNSKPILKFSVSAILGD--TREG-VRVRNEFMQPQHIWPYLQQNFMQ 190
            |....||: :..:|:....:|||.|.||:.:|:|:  ||.. :||......|
  Fly    27 VAASSTSV-SASSTVSASASSKPKLAFSIDSIVGESSTRSAPLRVSVISSPP------------- 77

  Fly   191 QHSHQYQQHHQQQQPHSHPQHQPLAVPGHQHSHPHSHHHHHHHPGAGHAHFPHPAFLTHQLPPHQ 255
                          |.|.....|..........|..:.:.........:..|..:.::....|
  Fly    78 --------------PRSESPASPTNTNNSGRRTPRGYIYCRRRDSLDRSRSPQRSPVSRSPSP-- 126

  Fly   256 HHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDSDNNHGASTANGNGSGTGNS----------- 309
                              |....:.::.|:|....|.:          |||||.
  Fly   127 ------------------PNAGGNPAAAGNTAKSGDPS----------SGTGNPPTLIRPLPLPA 163

  Fly   310 ------GQDARPHELA---------NSNPDEDSSASRRLT--------QDKQQQQQLLGAGGTGG 351
                  |....|:.:|         .|.|....:|..::.        |.:|||||.|....|
  Fly   164 PNLALIGNRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPT-- 226

  Fly   352 GGGGGHGHG-HPTPPPPPPPPVI--AKPMPSRPTPFLPHTL-NHPHLHSLLAHCRNPY------M 406
                |..|| ||..||...|..|  ..|.|..|.|...|.. :.|||      .|:.|      :
  Fly   227 ----GPPHGPHPHLPPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHL------IRDSYPLYPWLL 281

  Fly   407 SVGAQVFPLPPG----QGFPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKL 467
            |...::||..||    |.|       .||:|   .|..||.:|...||..|:...|:...:||:|
  Fly   282 SRHGRIFPRFPGNFLFQPF-------RKPKR---VRTAFSPTQLLKLEHAFEGNHYVVGAERKQL 336

  Fly   468 AERLGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSP 532
            |:.|.|.::|||:||||||     :|.:.:...||....|..||
  Fly   337 AQGLSLTETQVKVWFQNRR-----TKHKRMQQEGGDGSDTKSNK--------------------- 375

  Fly   533 SLLSPNGSATPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPLLTSLKMGDQS 597
                  ||::....|...:|:    |....|..|......|
  Fly   376 ------GSSSGGGGGGDGEDD----AKHDGSQHSYEDAEDP------------------------ 406

  Fly   598 ASATPTPLPGTTVSSAAASPPGVTASEFQAKINAEMQKQLVAADLKFKLENSIQEAKQRRFEQLQ 662
                                      |.:.:|..:.:.:::..| .:..|...:| .||..||.|
  Fly   407 --------------------------EDEDEIEEDDEDEVIDMD-DYGSEMDAEE-HQRLREQFQ 443

  Fly   663 QQL-HHSPHFSAMREVELAAAAAAAQLHHHHQQQQQQQQQQHAQQQHAQQQHQGGSEFMKLY 723
            ||| .|...|....      |..||.|....|.|..||.|||.||||.|||.....:..:||
  Fly   444 QQLAQHQQQFMQQN------AGEAATLSPQQQHQLLQQHQQHLQQQHHQQQQHFIQQQQQLY 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	23/53 (43%)
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	25/63 (40%)