Protein Alignment Dbx and HOXB7

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_004493.3
• Gene: HOXB7 / 3217
• HGNCID: 5118
• Length: 217
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 57/247 - (23%)
• Similarity: 78/247 - (31%)
• Gaps: 101/247 - (40%)

  Fly   277 ASSSSSPGSTISDSDNNHGASTANGNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQ 341
            ||:...||         :||    |:|:....|.|...|
Human    35 ASNPQRPG---------YGA----GSGASFAASMQGLYP-------------------------- 60

  Fly   342 QLLGAGGTGGGGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYM 406
               |.||..|....|               |.|......|:.|..|..  |...:|...|
Human    61 ---GGGGMAGQSAAG---------------VYAAGYGLEPSSFNMHCA--PFEQNLSGVC----- 100

  Fly   407 SVGAQVFPLPPGQG----------------------FPWAHSTRGKPRRGMMRRAVFSDSQRKGL 449
                      ||..                      :||..|:....:||   |..::..|...|
Human   101 ----------PGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRG---RQTYTRYQTLEL 152

  Fly   450 EKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELLASG 501
            ||.|...:|:::..|.::|..|.|.:.|:|||||||||||:  ||.:....|
Human   153 EKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWK--KENKTAGPG 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	23/53 (43%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		2/4 (50%)
		Homeodomain	138..194	CDD:459649	25/60 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..217		3/9 (33%)