Protein Alignment Dbx and HOXA9

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 68/265 - (25%)
• Similarity: 91/265 - (34%)
• Gaps: 78/265 - (29%)

  Fly   295 GASTANGNGSG---TGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGG 356
            ||..|:....|   .|..||..|.......:||....:.       |.:..:.||........|.
Human    18 GADAADELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSF-------QSKATVFGASWNPVHAAGA 75

  Fly   357 ---------HGHGHPTPPPPPPPPVIA----------KPMP----------SRPTPFLPHTLN-- 390
                     |.|.||...|..|....|          :|.|          |||....|..|:
Human    76 NAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSAR 140

  Fly   391 -------HPHLHSLLAH-CRNPYM------SVGA---------------QVFPLPPGQGFPWAHS 426
                   ..|..||..: |.:|.:      |.||               .:.|..|...:..|.|
Human   141 RGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARS 205

  Fly   427 TRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRN 491
            ||.|       |..::..|...|||.|....|:::..|.::|..|.|.:.||||||||||||.:.
Human   206 TRKK-------RCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 263

  Fly   492 -SKER 495
             :|:|
Human   264 INKDR 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	23/53 (43%)
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	36/181 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		7/42 (17%)
		Homeodomain	207..263	CDD:459649	25/62 (40%)