Protein Alignment Dbx and Vax2

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_036042.1
• Gene: Vax2 / 24113
• MGIID: 1346018
• Length: 292
• Species: Mus musculus
• Alignment Length: 361
• Identity: 92/361 - (25%)
• Similarity: 134/361 - (37%)
• Gaps: 102/361 - (28%)

  Fly   290 SDNNHGASTANGNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGG- 353
            ::.:.|.......|..:|..|:    |..|.....:..|||.|         ::.|...:...|
Mouse     6 AERDRGPKRREEPGGRSGRHGE----HRGAEDLRADTGSASPR---------EIAGTSASSPAGS 57

  Fly   354 --GGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYM--SVGA-QVF 413
              .||...|...                     |..|          .|||...:  :.|. :..
Mouse    58 RESGGDSDGQQA---------------------LGET----------DHCRRILVRDAKGTIREI 91

  Fly   414 PLPPGQGFPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQV 478
            .||.|...       .:|:|   .|..|:..|...||..||:.:|:...:|.:||.:|.|.::||
Mouse    92 VLPKGLDL-------DRPKR---TRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQV 146

  Fly   479 KIWFQNRRMKWRNSKEREL-LASGGSRDQTLPNKNNPNPDLSDAKCDRPLT-PLSPSLLSPNGSA 541
            |:||||||.|.:..:.|:| ..:..|..:.....|    .|...:..|.|: |.:||||    :.
Mouse   147 KVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSN----VLRLLEQGRLLSVPRAPSLL----AL 203

  Fly   542 TPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPLLTSLKMGDQSASAT---PT 603
            ||..||..|... .|:.|.|::       |||.:       :|.|          ||||:   |.
Mouse   204 TPGLPGLPASHR-GTSLVDPRN-------SSPRL-------NPMP----------SASASSPLPP 243

  Fly   604 PLPGTTVSSAAA--SPPG--VTASEFQAKINAEMQK 635
            |||....|||..  .|.|  :.:|.|:.....|.||
Mouse   244 PLPAICFSSAPLLDLPAGYKLGSSAFEPYSRLEQQK 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	23/53 (43%)
Vax2	NP_036042.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..74		17/111 (15%)
		Homeodomain	103..159	CDD:459649	24/58 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..242		15/59 (25%)