Protein Alignment Dbx and Nkx2-3

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_032725.1
• Gene: Nkx2-3 / 18089
• MGIID: 97348
• Length: 362
• Species: Mus musculus
• Alignment Length: 166
• Identity: 56/166 - (33%)
• Similarity: 71/166 - (42%)
• Gaps: 54/166 - (32%)

  Fly   428 RGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNS 492
            |.|||.....|.:||.:|...||:||:||:|:|.|:|:.||..|.|..:||||||||||.|.:..
Mouse   139 RPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQ 203

  Fly   493 KERELLASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSPSLLSPNGSATPPPPGAVA-----KD 552
            ::.:.|..|                                     ..|.||||..||     :|
Mouse   204 RQDKSLELG-------------------------------------THAPPPPPRRVAVPVLVRD 231

  Fly   553 EPPTAAVTPK-----SPQSV-----SSRSSPSVGYG 578
            ..|  .|||.     ||..|     |..|.|:.|||
Mouse   232 GKP--CVTPSAQTYGSPYGVGAGAYSYNSFPAYGYG 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	29/53 (55%)
Nkx2-3	NP_032725.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..149		4/9 (44%)
		Homeodomain	146..202	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..222		7/55 (13%)