Protein Alignment Dbx and DLX4

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Alignment Length: 194
• Identity: 57/194 - (29%)
• Similarity: 87/194 - (44%)
• Gaps: 30/194 - (15%)

  Fly   356 GHGHGHP-TPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYMSVGAQVFPLPPGQ 419
            ||...:| |.|..|....::...|:..:..|.....||  ..|.|....|.:|.       .|.:
Human    52 GHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHP--QELEADSEKPRLSP-------EPSE 107

  Fly   420 GFPWAHSTR-GKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQ 483
            ..|.|.:.: .||      |.::|..|.:.|.:|||..:|::.|:|.:||.:|||..:|||||||
Human   108 RRPQAPAKKLRKP------RTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQ 166

  Fly   484 NRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSPSLLSPNGSATPPPPG 547
            |:|.|::    :.|..:.|.::...|.:.     .|.:.|..||    |||.....:.|.|..|
Human   167 NKRSKYK----KLLKQNSGGQEGDFPGRT-----FSVSPCSPPL----PSLWDLPKAGTLPTSG 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	25/53 (47%)
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		10/48 (21%)
		Homeodomain	118..174	CDD:459649	27/65 (42%)