Protein Alignment Dbx and Evx2

DIOPT Version :10

• Sequence 1: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_031993.1
• Gene: Evx2 / 14029
• MGIID: 95462
• Length: 475
• Species: Mus musculus
• Alignment Length: 414
• Identity: 97/414 - (23%)
• Similarity: 138/414 - (33%)
• Gaps: 109/414 - (26%)

  Fly   243 HPAFLTHQLPPHQHH------------QQQQHVQQQHPGNSCQPQTASS--SSSPGSTISDSDNN 293
            |||.|:.:||....|            :.......|||.:.   .|.||  :|:..|....|..:
Mouse    45 HPARLSPRLPSAPLHGALGDLPAKGKFEIDTLFNLQHPSSE---STVSSEIASATESRKKPSHYS 106

  Fly   294 HGASTAN-------GNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGG 351
            ..|:.|:       |..:....||..|.|.:..|:....:|.:....|......    |.|...|
Mouse   107 EAAAEADMSSDVEVGCSALRSPSGLGAAPLKENNAKGYTESGSVAGTTTSASGS----GLGSLHG 167

  Fly   352 GGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYMSVGAQVFPLP 416
            |||||:.                                                  ||...
Mouse   168 GGGGGNS--------------------------------------------------GAAAL--- 179

  Fly   417 PGQGFPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIW 481
            .|.|   :.|...:.||   .|..|:..|...|||.|.::.|:|:|.|.:||..|.|.::.:|:|
Mouse   180 GGSG---SGSGADQVRR---YRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVW 238

  Fly   482 FQNRRMKWRNSKERELLASGGSRDQTLPNKNNPN-------PDLSDAKCDRPLTPLSPSLLSPNG 539
            |||||||    .:|:.||      .:.|:..:|:       ...:......|.....|....|:.
Mouse   239 FQNRRMK----DKRQRLA------MSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHV 293

  Fly   540 SATPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPLLTSLK-MGDQSASATPT 603
            ..|.....|.|..    ||....||.:.|.|...:........|.|.||.|.: .|...|.|...
Mouse   294 GVTAAAAAAAASG----AAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAA 354

  Fly   604 PLPGTTVSSAAASPPGVTASEFQA 627
            .|.....::|||:.....||...|
Mouse   355 GLNSAASAAAAAAAAAAAASSAAA 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	24/53 (45%)
Evx2	NP_031993.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..113		8/33 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..189		13/93 (14%)
		Homeodomain	192..248	CDD:459649	26/62 (42%)