DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsb and Snmp2

DIOPT Version :9

Sequence 1:	NP_001097477.1	Gene:	dsb / 38252	FlyBaseID:	FBgn0035290	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_001163372.1	Gene:	Snmp2 / 38868	FlyBaseID:	FBgn0035815	Length:	556	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	110/501 - (21%)
Similarity:	197/501 - (39%)	Gaps:	95/501 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 KLYIYNVTNPDGFLRGEKPHLQEVGPFVYREDMQKVNVKFHENNYTVSYQHKKILQF-----VPE 191
            |:||:||||.|...:|..|.::|:||:||::..||....|..:...:||.......|     .|.
  Fly    61 KVYIFNVTNSDRIQQGAIPIVEEIGPYVYKQFRQKKVKHFSRDGSKISYVQNVHFDFDAVASAPY 125

  Fly   192 LSIDK---------------DTPIT----------------TPNI---------------PLLTL 210
            ...|:               :..||                ||.:               .:|.:
  Fly   126 TQDDRIVALNMHMNAFLQVFEREITDIFQGFANRLNSRLNQTPGVRVLKRLMERIRGKRKSVLQI 190

  Fly   211 TSLSPKLGYL---LSKTISVVVTAAQFKPFINVTAEQLAF----------GYDDALVSLAHRFYP 262
            :...|.|..|   |:..:..|....: ..|::.:..:..|          |...|:.:.......
  Fly   191 SENDPGLALLLVHLNANLKAVFNDPR-SMFVSTSVREYLFDGVRFCINPQGIAKAICNQIKESGS 254

  Fly   263 KHMRPMERMGLLLG----RNGTLTEVSSVKTGMDSMDQFGYIDQLNGLDHLPHW----SE---PP 316
            |.:|......|...    :||:..||..|.||.....:...|.:|:...:|..|    ||   ..
  Fly   255 KTIREKSDGSLAFSFFGHKNGSGHEVYEVHTGKGDPMRVLEIQKLDDSHNLQVWLNASSEGETSV 319

  Fly   317 CTSIAGSEGSFFPP-RELTKSEVVHIYDKDLCRIIPLKYVESLEKDGIAADLFRLPNNSYGDSAH 380
            |..|.|::.|.:|| |:  :.:.::|:..|:||.:.|.|...::..||....:.:..|...|...
  Fly   320 CNQINGTDASAYPPFRQ--RGDSMYIFSADICRSVQLFYQTDIQYQGIPGYRYSIGENFINDIGP 382

  Fly   381 NPENKCYDTSEYEPI---------QGLQNISPCQYGAPVYISNPHFFESHPDLLNSVEGLKPERE 436
            ..:|:|:...:...:         .|..:::.| ..|||.::.||...:..:....:.||||:.:
  Fly   383 EHDNECFCVDKLANVIKRKNGCLYAGALDLTTC-LDAPVILTLPHMLGASNEYRKMIRGLKPDAK 446

  Fly   437 KHETYFKIQPKLGVPLEGKVRIQLNLKVTRAKDVYPVRDFRDFVFPVMWLEEGI---SELTPAIK 498
            ||:|:..:|...|.||:|..|:|.|:.:.....:....:....:.|.:|:||||   .|:....|
  Fly   447 KHQTFVDVQSLTGTPLQGGKRVQFNMFLKSINRIGITENLPTVLMPAIWVEEGIQLNGEMVAFFK 511

  Fly   499 RWIYLGTVIAPSAVPIGSYLMILGGAFAIIFSFVRAYQNFMFAQDP 544
            :.: :.|:...:.|...:....:|.|.|.:..::  ||.....:.|
  Fly   512 KKL-INTLKTLNIVHWATLCGGIGVAVACLIYYI--YQRGRVVEPP 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsb	NP_001097477.1	CD36	103..532	CDD:279474	107/487 (22%)
Snmp2	NP_001163372.1	CD36	10..543	CDD:395898	107/486 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450747
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	6	5.850