DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsb and scarb1

DIOPT Version :9

Sequence 1:	NP_001097477.1	Gene:	dsb / 38252	FlyBaseID:	FBgn0035290	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	XP_017213428.1	Gene:	scarb1 / 387260	ZFINID:	ZDB-GENE-031126-1	Length:	511	Species:	Danio rerio

Alignment Length:	469	Identity:	134/469 - (28%)
Similarity:	234/469 - (49%)	Gaps:	22/469 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 ISNNRLAVI--IIGIITLILGIILSSMP--WLDYFILKNLRL--WNDTLSYHYWQRPGVIRLTKL 133
            :|...::::  ::|.:.|:.|.:|..:.  .:|..|:||:.:  .|| |||..|:...|.....:
Zfish     2 VSQTTVSIVFLVLGGMALLFGTVLVFVGPIIIDDQIVKNVEINPKND-LSYTMWKDIPVPFFMSV 65

  Fly   134 YIYNVTNPDGFLRGEKPHLQEVGPFVYREDMQKVNVKFHENNYTVSYQHKKILQFVPELSI-DKD 197
            |.:::.|||..|:||:|.:.:.||:||||:..|.|:.||| |:||||:..:...|...:|: |:.
Zfish    66 YFFHIVNPDEILKGERPMVIQRGPYVYRENRWKDNITFHE-NHTVSYKEYRQYFFEESMSVGDES 129

  Fly   198 TPITTPNIPLLTLTSLSPKLGYLLSKTISVVVTAAQFKPFINVTAEQLAFGYDDALVSLAHRFYP 262
            ..:|.||:.:|..:.:...:.:.:...:|.........||:.....:|.:|||..||...:::.|
Zfish   130 DVVTIPNMLVLGASVMMENMPFPVRLLLSTTFKTFNEGPFLTKPVGELMWGYDSKLVDFLNKYLP 194

  Fly   263 KHMRPMERMGLLLGRNGTLTEVSSVKTGMDSMDQFGYIDQLNGLDHLPHWSEPPCTSIAGSEGSF 327
            ..:....:.||....|.:.|.:.::.||.|.:.:...:|..|||.::.:|....|..|.|:.|..
Zfish   195 GMLPSSGKFGLFADFNNSNTGLFTIFTGRDDIRKVHMVDSWNGLKNVDYWRSDQCNMINGTAGQM 259

  Fly   328 FPPRELTKSEVVHIYDKDLCRIIPLKYVESLEKDGIAADLFRLPNNSYGDSAHNPENK----CYD 388
            :|| .:||...:..|..|.||.:.|.|...|...||....:..|...:.:.|..|.|:    |..
Zfish   260 WPP-FMTKETTMPFYSPDACRSMELVYQRPLVSSGIPVYRYVSPKTLFANGADFPPNEGFCPCRQ 323

  Fly   389 TSEYEPIQGLQNISPCQYGAPVYISNPHFFESHPDLLNSVEGLKPEREKHETYFKIQPKLGVPLE 453
            :       ||.|:|.|::|:|.:||.|||:.:.|.||::|.||.|..::|..:..|.|:.|||:.
Zfish   324 S-------GLLNVSSCRHGSPTFISQPHFYNADPQLLDTVSGLSPSEDEHGLFIDIHPETGVPVN 381

  Fly   454 GKVRIQLNLKVTRAKDVYPVRDFRDFVFPVMWLEEGISELTPAIKRWIYLGTVIAPSAVPIGSYL 518
            ..||:||||.:.:...:....:..:.|.|::|.||. ..:...:........|:.|..:....|:
Zfish   382 VSVRLQLNLFLKKVSGISETGNIAEVVMPMLWFEES-GYIDGPVLHTFRTNLVVLPKVMEYMQYI 445

  Fly   519 MILGGAFAIIFSFV 532
            .|..|..||:.:.:
Zfish   446 FIALGLAAILTAVI 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsb	NP_001097477.1	CD36	103..532	CDD:279474	129/435 (30%)
scarb1	XP_017213428.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582137
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0000618
OrthoInspector	1	1.000	-	-		mtm6350
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.960