Protein Alignment dsb and Cd36

DIOPT Version :10

• Sequence 1: NP_001097477.1
• Gene: dsb / 38252
• FlyBaseID: FBgn0035290
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_113749.2
• Gene: Cd36 / 29184
• RGDID: 2301
• Length: 472
• Species: Rattus norvegicus
• Alignment Length: 481
• Identity: 127/481 - (26%)
• Similarity: 223/481 - (46%)
• Gaps: 60/481 - (12%)

  Fly    84 IIGIITLILGIILSSMPWLDYFILKNLR----LWNDTLSYHYWQRPGVIRLTKLYIYNVTNPDGF 144
            :||.:..:.|.||  ||..|..|.|.::    |...|:::..|.:.|.....:.:|::|.||:..
  Rat    14 VIGAVLAVFGGIL--MPVGDLLIEKTIKREVVLEEGTIAFKNWVKTGTTVYRQFWIFDVQNPEEV 76

  Fly   145 LR-GEKPHLQEVGPFVYR-EDMQKVNVKFHENNYTVSYQHKKILQFVPELSIDKDTPITTPNIPL 207
            .: ..|..:::.||:.|| ..:.|.|:.....:.|||:.......|.|.||:..:    ..|..:
  Rat    77 AKNSSKIKVKQRGPYTYRVRYLAKENITQDPKDSTVSFVQPNGAIFEPSLSVGTE----NDNFTV 137

  Fly   208 LTL-TSLSPKL--GYLLSKTISVVVTAAQFKPFINVTAEQLAFGYDDALVSLAHRFYPKHMRPME 269
            |.| .:.:|.:  ...:...::.::..::...|...:.::|.:||.|..:||..  ||    ...
  Rat   138 LNLAVAAAPHIYTNSFVQGVLNSLIKKSKSSMFQTRSLKELLWGYKDPFLSLVP--YP----IST 196

  Fly   270 RMGLLLGRNGTLTEVSSVKTGMDSMDQFGYIDQLNGLDHLPHWSEPPCTSIAGSEGSFFPPRELT 334
            .:|:....|.|:..|..|..|.|::.:...||...|..:|.:| |..|..|.|::.:.||| .:.
  Rat   197 TVGVFYPYNNTVDGVYKVFNGKDNISKVAIIDTYKGKRNLSYW-ESYCDMINGTDAASFPP-FVE 259

  Fly   335 KSEVVHIYDKDLCRIIPLKYVESLEKDGIAADLFRLPNNSYGDSAHNPENKCYDT--------SE 391
            ||..:..:..|:||.|...:...:...||....|.||.|::.....||:|.|:.|        :.
  Rat   260 KSRTLRFFSSDICRSIYAVFGSEVNLKGIPVYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTS 324

  Fly   392 YEPIQGLQNISPCQYGAPVYISNPHFFESHPDLLNSVEGLKPEREKHETYFKIQPKLGVPLEGKV 456
            |    |:.:|..|:.|.|||||.|||..:.||:...:|||.|..::|.||..::|..|..|:...
  Rat   325 Y----GVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLNPNEDEHRTYLDVEPITGFTLQFAK 385

  Fly   457 RIQLNLKVTRAKDVYPVRDF-RDFVFPVMWLEE-GI----------SELTPAIKRWIYLGTVIAP 509
            |:|:|:.|..|:.:..:::. |.::.|::||.| |.          :::|..||   .||.|
  Rat   386 RLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFRNQVTGKIK---LLGLV--- 444

  Fly   510 SAVPIGSYLMILGGAFAIIFSFVRAY 535
                   .:::||....:..:|:.:|
  Rat   445 -------EMVLLGVGVVMFVAFMISY 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsb	NP_001097477.1	CD36	103..534	CDD:460076	119/459 (26%)
Cd36	NP_113749.2	CD36	14..463	CDD:460076	126/479 (26%)
		Required for interaction with thrombospondins, THBS1 and THBS2. /evidence=ECO:0000250	93..120		7/26 (27%)
		Interaction with PTK2, PXN and LYN. /evidence=ECO:0000250|UniProtKB:P16671	460..472		1/4 (25%)