Protein Alignment dsb and Scarb2

DIOPT Version :9

• Sequence 1: NP_001097477.1
• Gene: dsb / 38252
• FlyBaseID: FBgn0035290
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_031670.1
• Gene: Scarb2 / 12492
• MGIID: 1196458
• Length: 478
• Species: Mus musculus
• Alignment Length: 461
• Identity: 148/461 - (32%)
• Similarity: 241/461 - (52%)
• Gaps: 29/461 - (6%)

  Fly    82 VIIIGIITLILGIILSSMPWLDYFILKNLRLWNDTLSYHYWQRPGVIRLTKLYIYNVTNPDGFLR 146
            ::::..:||::..:....  :|..|.||:.|.|.|..::.|::|.:....:.|.:|||||:..|:
Mouse    15 LLLVTSVTLLVARVFQKA--VDQTIEKNMVLQNGTKVFNSWEKPPLPVYIQFYFFNVTNPEEILQ 77

  Fly   147 GEKPHLQEVGPFVYREDMQKVNVKFHENNYTVSYQHKKILQFVPELSI-DKDTP-ITTPNIPLLT 209
            ||.|.|:||||:.|||...|.|::|.||..|:|....|...|....|: |.:.. |.|.||||||
Mouse    78 GEIPLLEEVGPYTYRELRNKANIQFGENGTTISAVTNKAYVFERNQSVGDPNVDLIRTINIPLLT 142

  Fly   210 LTSLSPKLGYLLSKTISVVVTAAQFKPFINVTAEQLAFGYDDALVSLAHRFYPKHMRPMERMGLL 274
            :..|:...  ||.:.|..::.|.|.|.|:..|..:|.:||.|.::||.|.|.| .:.|  ..||.
Mouse   143 VVDLAQLT--LLRELIEAMLKAYQQKLFVIHTVHELLWGYKDEILSLVHIFKP-DVSP--NFGLF 202

  Fly   275 LGRNGTLTEVSSVKTGMDSMDQFGYIDQLNGLDHLPHWSEPPCTSIAGSEGSFFPPRELTKSEVV 339
            ..||||........||.|:...|..|.:.||...|..|:...|..|.|::|..|.|. ::|.||:
Mouse   203 YERNGTNDGEYVFLTGEDNYLNFSKIVEWNGKTSLDWWTTDTCNMINGTDGDSFHPL-ISKDEVL 266

  Fly   340 HIYDKDLCRIIPLKYVESLEKDGIAADLFRLPNNSYGDSAHN-----PENKCYDTSEYEPIQGLQ 399
            :::..||||.:.:.:......:|:.|..:::|.....:::.|     ||..|.|:       |:.
Mouse   267 YLFPSDLCRSVHITFSSFENVEGLPAFRYKVPAEILANTSENAGFCIPEGNCMDS-------GVL 324

  Fly   400 NISPCQYGAPVYISNPHFFESHPDLLNSVEGLKPEREKHETYFKIQPKLGVPLEGKVRIQLNLKV 464
            |||.|:.|||:.:|.|||:::....:::::|:.|.:|:||::..|.|..|:.|.|..|.|:|..|
Mouse   325 NISICKNGAPIIMSFPHFYQADEKFVSAIKGMHPNKEEHESFVDINPLTGIILRGAKRFQINTYV 389

  Fly   465 TRAKDVYPVRDFRDFVFPVMWLEEGI---SELTPAIKRWIYLGTVIAPSAVPIGSYLMILGGAFA 526
            .:..|.....|.|..|||||:|.|.:   .|....:|.  .:.|.:..:.:|.  .:|.||..|.
Mouse   390 RKLDDFVETGDIRTMVFPVMYLNESVLIDKETANQLKS--VINTTLVVTNIPY--IIMALGVFFG 450

  Fly   527 IIFSFV 532
            ::|:::
Mouse   451 LVFTWL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsb	NP_001097477.1	CD36	103..532	CDD:279474	146/438 (33%)
Scarb2	NP_031670.1	CD36	28..455	CDD:279474	146/445 (33%)
		Important for interaction with GBA	155..191		13/35 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5605
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0000618
OrthoInspector	1	1.000	-	-		mtm8809
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.880