Protein Alignment CG13937 and CHST12

DIOPT Version :10

• Sequence 1: NP_728688.2
• Gene: CG13937 / 38249
• FlyBaseID: FBgn0035287
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: XP_047276527.1
• Gene: CHST12 / 55501
• HGNCID: 17423
• Length: 463
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 95/394 - (24%)
• Similarity: 164/394 - (41%)
• Gaps: 73/394 - (18%)

  Fly    76 HGQFPYPVVRYPVLLLNKNKNKDLTV-----------VATG-KTKNKWRYVDKDSNQTLLPLIPE 128
            |..|..|....|:.....:::::||.           ::.| |..:..|   |::.|...|...|
Human    86 HTSFSRPHTGPPLPTPGPDRDRELTADSDVDEFLDKFLSAGVKQSDLPR---KETEQPPAPGSME 147

  Fly   129 HAVQ--TLTPQEMLQVEQRMDQRRER---LKDKCSAYGL----------DVLGHDAWHTPNTWEF 178
            .:|:  ..:|::..:...:..|:.||   |:..|:...|          |:...:..|      .
Human   148 ESVRGYDWSPRDARRSPDQGRQQAERRSVLRGFCANSSLAFPTKERAFDDIPNSELSH------L 206

  Fly   179 LVNKKYHIIWCNVFKAASSSWMFNFNVLAGYSPSYLRK------------------TKKILLNLA 225
            :|:.::..|:|.|.|.|.::|.....||:|   |.|.:                  :..:..|..
Human   207 IVDDRHGAIYCYVPKVACTNWKRVMIVLSG---SLLHRGAPYRDPLRIPREHVHNASAHLTFNKF 268

  Fly   226 RERYPRVTLDELREAQNYSVTFIIARDPFERLLSAYRDKMVFALP-YSFHDKLGRSIVRNYRKKP 289
            ..||.:::...::........|:..||||.||:||:|.|  |.|. ..|:.|....::|.|....
Human   269 WRRYGKLSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSK--FELENEEFYRKFAVPMLRLYANHT 331

  Fly   290 SLAARA-----ANTKFPSFPEFVHWLLD-QVKRGSFIDMHFVAATSFCTPCLIRFDMILKFESLA 348
            ||.|.|     |..|. ||..|:.:||| ..::.:..:.|:......|.||.|.:|.:.|.|:|.
Human   332 SLPASAREAFRAGLKV-SFANFIQYLLDPHTEKLAPFNEHWRQVYRLCHPCQIDYDFVGKLETLD 395

  Fly   349 EDQLYLIEKTGLKRVI--APVWRNMGKGRKTHELQQQFYAQLTRQEMLELYEYYKYDFELFDYDI 411
            ||...|::...:.|.:  .|.:||    |.....::.::|::......:||:.|:.||.||.|..
Human   396 EDAAQLLQLLQVDRQLRFPPSYRN----RTASSWEEDWFAKIPLAWRQQLYKLYEADFVLFGYPK 456

  Fly   412 QEYL 415
            .|.|
Human   457 PENL 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13937	NP_728688.2	Sulfotransfer_2	181..410	CDD:427369	68/255 (27%)
CHST12	XP_047276527.1	Sulfotransfer_2	209..455	CDD:427369	68/255 (27%)