Protein Alignment CG12025 and TMEM134

DIOPT Version :9

• Sequence 1: NP_001261296.1
• Gene: CG12025 / 38246
• FlyBaseID: FBgn0035285
• Length: 170
• Species: Drosophila melanogaster
• Sequence 2: XP_024304465.1
• Gene: TMEM134 / 80194
• HGNCID: 26142
• Length: 222
• Species: Homo sapiens
• Alignment Length: 162
• Identity: 45/162 - (27%)
• Similarity: 71/162 - (43%)
• Gaps: 26/162 - (16%)

  Fly    34 PMRGKQGRSTEDVSIRIQD--------PKGYNKYAEDTTSRDSDSLIQEYGNLPTEETNTYC--- 87
            |:|.:.|.|...:...:..        |......|..|.:....:.:....:.|.......|
Human    59 PLRSRMGESAPGIPAELPSAAPSGPSAPSAAAPSAPTTPAAGEPARLSPQPSSPGSTPTASCTPS 123

  Fly    88 --------------W-RHPKVRENWRTVLAAFTLLVVGTGLFVMGTFAIADPQNTSQGVVFFVAG 137
                          | :||.:::|.|.|||:|.||::|..|.::|....|.|.......:|||.|
Human   124 LHLLHIHPALLPPSWTQHPLIQKNRRVVLASFLLLLLGLVLILVGVGLEATPSPGVSSAIFFVPG 188

  Fly   138 LICFIPGAYHVVYIWLAAKGYRGFDFYHLPLF 169
            .:..:||.|||::|:.|.||:|||.|::||.|
Human   189 FLLLVPGVYHVIFIYCAVKGHRGFQFFYLPYF 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12025	NP_001261296.1	DUF872	61..169	CDD:399128	38/125 (30%)
TMEM134	XP_024304465.1	DUF872	<136..220	CDD:310477	35/83 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156706
Domainoid	1	1.000	83	1.000	Domainoid score	I8393
eggNOG	1	0.900	-	-		E1_KOG4753
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I5196
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008408
OrthoInspector	1	1.000	-	-		oto88855
orthoMCL	1	0.900	-	-		OOG6_110165
Panther	1	1.100	-	-	LDO	PTHR13558
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5767
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.780