Protein Alignment Rap1 and DIRAS3

DIOPT Version :10

• Sequence 1: NP_476857.1
• Gene: Rap1 / 38244
• FlyBaseID: FBgn0004636
• Length: 184
• Species: Drosophila melanogaster
• Sequence 2: NP_004666.1
• Gene: DIRAS3 / 9077
• HGNCID: 687
• Length: 229
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 70/196 - (35%)
• Similarity: 109/196 - (55%)
• Gaps: 13/196 - (6%)

  Fly     1 MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFT 65
            :|:|::||:|:.|||||.|..::....|..:|.||||::|.:.:........|.|.|:...:...
Human    35 IRDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDGNR 99

  Fly    66 AMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTD--DVPMVLVGNKCDLEEERVVGK 128
            |::...:..|..||||||:|.:.|..:|:...|.|.::|..:  ..|:||||||.| :..|.|..
Human   100 ALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSD-DTHREVAL 163

  Fly   129 ELGKNLATQFNCAFMETSAKAKVNVNDIFYDLVRQINK-----KSPEKKQKKP---KKSL--CVL 183
            ..|...|.::||||||.|||..|||.::|:.|:....|     :.||||.:.|   :|.|  |::
Human   164 NDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGLQEPEKKSQMPNTTEKLLDKCII 228

  Fly   184 L 184
            :
Human   229 M 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_476857.1	Rap1	3..165	CDD:133375	60/163 (37%)
DIRAS3	NP_004666.1	P-loop containing Nucleoside Triphosphate Hydrolases	37..200	CDD:476819	60/163 (37%)
		Effector region. /evidence=ECO:0000255	66..74		5/7 (71%)