DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap1 and Rras2

DIOPT Version :9

Sequence 1:	NP_001189023.1	Gene:	Rap1 / 38244	FlyBaseID:	FBgn0004636	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_080122.2	Gene:	Rras2 / 66922	MGIID:	1914172	Length:	204	Species:	Mus musculus

Alignment Length:	190	Identity:	96/190 - (50%)
Similarity:	133/190 - (70%)	Gaps:	9/190 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAM 67
            :|::||:|.|||||||||:||:|..||..|||||||||.||..:|.:...|:||||||.|:|.||
Mouse    14 KYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAM 78

  Fly    68 RDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGK 132
            |:.||:.|:||:||:|:|.:.:|.::...:.|||||||.|:.||:|:|||.||:.:|.|.:|.|:
Mouse    79 REQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQ 143

  Fly   133 NLATQFNCAFMETSAKAKVNVNDIFYDLVRQINK-------KSPE--KKQKKPKKSLCVL 183
            .||.|....:||.|||.::||:..|::|||.|.|       .|||  :|:|..|...||:
Mouse   144 QLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVI 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_001189023.1	Rap1	3..165	CDD:133375	86/161 (53%)
Rras2	NP_080122.2	M_R_Ras_like	13..176	CDD:133345	86/161 (53%)
Rras2	NP_080122.2	Effector region	43..51		7/7 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100217
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740