Protein Alignment Rap1 and RIT2

DIOPT Version :10

• Sequence 1: NP_476857.1
• Gene: Rap1 / 38244
• FlyBaseID: FBgn0004636
• Length: 184
• Species: Drosophila melanogaster
• Sequence 2: NP_002921.1
• Gene: RIT2 / 6014
• HGNCID: 10017
• Length: 217
• Species: Homo sapiens
• Alignment Length: 179
• Identity: 88/179 - (49%)
• Similarity: 128/179 - (71%)
• Gaps: 2/179 - (1%)

  Fly     2 REYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTA 66
            ||||:|:||:|||||||:|:||:...|.:.:||||||:|:.||.:|.:...|:||||||..:|||
Human    19 REYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQAEFTA 83

  Fly    67 MRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELG 131
            ||:.||:.|:||::.||:|.:.:|.:....:|.|.:|:.|.::|:||||||.|||:.|.|..|.|
Human    84 MREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLEQFRQVSTEEG 148

  Fly   132 KNLATQFNCAFMETSAKAKVNVNDIFYDLVRQINKKS--PEKKQKKPKK 178
            .:||.::||.|.||||..:..::|.|:.|||:|.||.  |...:||.|:
Human   149 LSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRKKESMPSLMEKKLKR 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_476857.1	Rap1	3..165	CDD:133375	80/161 (50%)
RIT2	NP_002921.1	Rit_Rin_Ric	19..190	CDD:206712	85/170 (50%)