Protein Alignment Rap1 and RAP1B

DIOPT Version :10

• Sequence 1: NP_476857.1
• Gene: Rap1 / 38244
• FlyBaseID: FBgn0004636
• Length: 184
• Species: Drosophila melanogaster
• Sequence 2: NP_056461.1
• Gene: RAP1B / 5908
• HGNCID: 9857
• Length: 184
• Species: Homo sapiens
• Alignment Length: 185
• Identity: 159/185 - (85%)
• Similarity: 171/185 - (92%)
• Gaps: 2/185 - (1%)

  Fly     1 MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFT 65
            |||||:|||||||||||||||||||.|||||||||||||||||||||.|||||||||||||||||
Human     1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFT 65

  Fly    66 AMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKEL 130
            |||||||||||||.||||||||||||||||||||||||||||||||:|||||||||:|||||||.
Human    66 AMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQ 130

  Fly   131 GKNLATQF-NCAFMETSAKAKVNVNDIFYDLVRQINKKSPEKKQKKPKKSLCVLL 184
            |:|||.|: ||||:|:|||:|:|||:||||||||||:|:| ...|..|||.|.||
Human   131 GQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTP-VPGKARKKSSCQLL 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_476857.1	Rap1	3..165	CDD:133375	146/162 (90%)
RAP1B	NP_056461.1	Rap1	3..167	CDD:133375	147/163 (90%)
		Interaction with KRIT1. /evidence=ECO:0000269|PubMed:22577140	25..67		39/41 (95%)
		Effector region. /evidence=ECO:0000305	32..40		7/7 (100%)