DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap1 and RALB

DIOPT Version :9

Sequence 1:	NP_001189023.1	Gene:	Rap1 / 38244	FlyBaseID:	FBgn0004636	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_001356329.1	Gene:	RALB / 5899	HGNCID:	9840	Length:	206	Species:	Homo sapiens

Alignment Length:	178	Identity:	90/178 - (50%)
Similarity:	130/178 - (73%)	Gaps:	2/178 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMR 68
            :|::::|||||||||||:||:...|||.|:||..|||||:|.:||::..::||||||.|.:.|:|
Human    15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIR 79

  Fly    69 DLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVK-DTDDVPMVLVGNKCDLEEERVVGKELGK 132
            |.|.::|:||:||:|||...:|....:.|||||||| :.|.:|:::||||.||||.|.|..|..:
Human    80 DNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEERRQVPVEEAR 144

  Fly   133 NLATQFNCAFMETSAKAKVNVNDIFYDLVRQI-NKKSPEKKQKKPKKS 179
            :.|.::...::|||||.:.||:.:|:||:|:| .||..|.|.|..|||
Human   145 SKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDKNGKKS 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_001189023.1	Rap1	3..165	CDD:133375	82/162 (51%)
RALB	NP_001356329.1	RalA_RalB	15..178	CDD:206710	82/162 (51%)
		Effector region	43..51		4/7 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	180..206		7/13 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810