DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap1 and hras

DIOPT Version :9

Sequence 1:	NP_001189023.1	Gene:	Rap1 / 38244	FlyBaseID:	FBgn0004636	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	XP_012816615.1	Gene:	hras / 549757	XenbaseID:	XB-GENE-479381	Length:	199	Species:	Xenopus tropicalis

Alignment Length:	189	Identity:	100/189 - (52%)
Similarity:	134/189 - (70%)	Gaps:	7/189 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFT 65
            |.|||:||:|:|||||||||:|.:|..||::|||||||||||||.:||:.|:|:||||||.|:::
Frog    11 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 75

  Fly    66 AMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKEL 130
            ||||.||:.|:||:.|::|....:|.|:...||||.||||:|||||||||||||| ..|.|....
Frog    76 AMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-PARTVETRQ 139

  Fly   131 GKNLATQFNCAFMETSAKAKVNVNDIFYDLVRQINK------KSPEKKQKKPKKSLCVL 183
            .::||..:...::|||||.:..|.|.||.|||:|.:      ..|::.:|......||:
Frog   140 AQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESEKGCLNCKCVV 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_001189023.1	Rap1	3..165	CDD:133375	94/161 (58%)
hras	XP_012816615.1	H_N_K_Ras_like	13..174	CDD:133338	94/161 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030