Protein Alignment Rap1 and KRAS

DIOPT Version :10

• Sequence 1: NP_476857.1
• Gene: Rap1 / 38244
• FlyBaseID: FBgn0004636
• Length: 184
• Species: Drosophila melanogaster
• Sequence 2: XP_047284782.1
• Gene: KRAS / 3845
• HGNCID: 6407
• Length: 227
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 102/190 - (53%)
• Similarity: 138/190 - (72%)
• Gaps: 7/190 - (3%)

  Fly     1 MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFT 65
            |.|||:||:|:|||||||||:|.:|..||::|||||||||||||.:||:.|:|:||||||.|:::
Human     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

  Fly    66 AMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKEL 130
            ||||.||:.|:||:.|::|....:|.|:...||||.||||::||||||||||||| ..|.|..:.
Human    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSRTVDTKQ 129

  Fly   131 GKNLATQFNCAFMETSAKAKVNVNDIFYDLVRQINK---KSPEKKQKKP---KKSLCVLL 184
            .::||..:...|:|||||.:..|.|.||.|||:|.:   |...|::|.|   |...|:::
Human   130 AQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_476857.1	Rap1	3..165	CDD:133375	94/161 (58%)
KRAS	XP_047284782.1	H_N_K_Ras_like	3..164	CDD:133338	94/161 (58%)