DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap1 and nras

DIOPT Version :9

Sequence 1:	NP_001189023.1	Gene:	Rap1 / 38244	FlyBaseID:	FBgn0004636	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_571220.2	Gene:	nras / 30380	ZFINID:	ZDB-GENE-990415-166	Length:	188	Species:	Danio rerio

Alignment Length:	183	Identity:	100/183 - (54%)
Similarity:	133/183 - (72%)	Gaps:	3/183 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFT 65
            |.|||:||:|:|||||||||:|.:|..||::|||||||||||||.:||:.|:|:||||||.|:::
Zfish     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

  Fly    66 AMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKEL 130
            ||||.||:.|:||:.|::|....:|.|:...||||.||||:||||||||||||||  .|.|..:.
Zfish    66 AMRDQYMRTGEGFLCVFAINNSKSFADVHLYREQIKRVKDSDDVPMVLVGNKCDL--ARTVDTKQ 128

  Fly   131 GKNLATQFNCAFMETSAKAKVNVNDIFYDLVRQINKKSPEK-KQKKPKKSLCV 182
            .:.||..:...|:|||||.:..|.|.||.|||:|.....:| ..::.:|..|:
Zfish   129 AQELARSYGIEFVETSAKTRQGVEDAFYTLVREIRHYRMKKLNSREDRKQGCL 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_001189023.1	Rap1	3..165	CDD:133375	95/161 (59%)
nras	NP_571220.2	H_N_K_Ras_like	3..163	CDD:133338	95/161 (59%)
		Effector region	32..40		7/7 (100%)
		Hypervariable region. /evidence=ECO:0000250	165..184		3/17 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100217
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.710