DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap1 and ras-1

DIOPT Version :9

Sequence 1:	NP_001189023.1	Gene:	Rap1 / 38244	FlyBaseID:	FBgn0004636	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_496623.1	Gene:	ras-1 / 174875	WormBaseID:	WBGene00004310	Length:	212	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	89/188 - (47%)
Similarity:	127/188 - (67%)	Gaps:	17/188 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRD 69
            :|||:|.|||||||||:||:|..||:.|||||||||.||..||...|.||||||||.|:|:.||:
Worm    19 RIVVVGGGGVGKSALTIQFIQRYFVQDYDPTIEDSYTKQCFVDEDLCKLEILDTAGQEEFSTMRE 83

  Fly    70 LYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNL 134
            .|::.|.||::|:::|.:::|.:::.|.|.|.|:||.||.|::|||||.|||.||.|.:...:.|
Worm    84 QYLRTGSGFLIVFAVTDRNSFEEVKKLHELICRIKDRDDFPIILVGNKADLENERHVARHEAEEL 148

  Fly   135 ATQFNCAFMETSAKAKVNVNDIFYDLVRQINK-----------------KSPEKKQKK 175
            |.:.:..::|.|||.:.||::.|:|:||.:.|                 :||.|.:||
Worm   149 AHRLSIPYLECSAKIRKNVDEAFFDIVRLVRKYQHDERMPIHPHDDRKLESPIKLKKK 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_001189023.1	Rap1	3..165	CDD:133375	83/159 (52%)
ras-1	NP_496623.1	small_GTPase	30..181	CDD:197466	75/150 (50%)
ras-1	NP_496623.1	M_R_Ras_like	30..179	CDD:133345	75/148 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100217
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840