Protein Alignment Rap1 and Hras

DIOPT Version :10

• Sequence 1: NP_476857.1
• Gene: Rap1 / 38244
• FlyBaseID: FBgn0004636
• Length: 184
• Species: Drosophila melanogaster
• Sequence 2: NP_032310.2
• Gene: Hras / 15461
• MGIID: 96224
• Length: 189
• Species: Mus musculus
• Alignment Length: 190
• Identity: 102/190 - (53%)
• Similarity: 135/190 - (71%)
• Gaps: 9/190 - (4%)

  Fly     1 MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFT 65
            |.|||:||:|:|||||||||:|.:|..||::|||||||||||||.:||:.|:|:||||||.|:::
Mouse     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

  Fly    66 AMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKEL 130
            ||||.||:.|:||:.|::|....:|.|:...||||.||||:|||||||||||||| ..|.|....
Mouse    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-AARTVESRQ 129

  Fly   131 GKNLATQFNCAFMETSAKAKVNVNDIFYDLVRQINKKSPEKKQKKPKKS-------LCVL 183
            .::||..:...::|||||.:..|.|.||.|||:| ::...:|...|.:|       .|||
Mouse   130 AQDLARSYGIPYIETSAKTRQGVEDAFYTLVREI-RQHKLRKLNPPDESGPGCMSCKCVL 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_476857.1	Rap1	3..165	CDD:133375	94/161 (58%)
Hras	NP_032310.2	H_N_K_Ras_like	3..164	CDD:133338	95/162 (59%)
		Effector region	32..40		7/7 (100%)
		Hypervariable region	166..185		3/18 (17%)