Protein Alignment Rap1 and DIRAS1

DIOPT Version :10

• Sequence 1: NP_476857.1
• Gene: Rap1 / 38244
• FlyBaseID: FBgn0004636
• Length: 184
• Species: Drosophila melanogaster
• Sequence 2: XP_047294230.1
• Gene: DIRAS1 / 148252
• HGNCID: 19127
• Length: 232
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 76/193 - (39%)
• Similarity: 123/193 - (63%)
• Gaps: 12/193 - (6%)

  Fly     3 EYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAM 67
            :|::||.|:||||||:|.::||:..|.:.|.|||||:||:.:..|...|.|:|.||.|:.||.||
Human    41 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAM 105

  Fly    68 RDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVK-DTDDVPMVLVGNKCDLEEERVVGKELG 131
            :.|.:..|..|:||:|:|::.:..:|..:.:.|:::| ..:|:|::||||||| |.:|.|.....
Human   106 QRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCD-ETQREVDTREA 169

  Fly   132 KNLATQFNCAFMETSAKAKVNVNDIFYDLV-------RQIN---KKSPEKKQKKPKKSLCVLL 184
            :.:|.::.|||||||||...||.::|.:|:       ..:|   |:|.::|:....|..|.|:
Human   170 QAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRSGKQKRTDRVKGKCTLM 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_476857.1	Rap1	3..165	CDD:133375	69/169 (41%)
DIRAS1	XP_047294230.1	P-loop containing Nucleoside Triphosphate Hydrolases	41..202	CDD:476819	69/161 (43%)