DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap1 and mrasb

DIOPT Version :9

Sequence 1:	NP_001189023.1	Gene:	Rap1 / 38244	FlyBaseID:	FBgn0004636	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	XP_003201047.1	Gene:	mrasb / 100317924	ZFINID:	ZDB-GENE-050208-495	Length:	209	Species:	Danio rerio

Alignment Length:	195	Identity:	94/195 - (48%)
Similarity:	131/195 - (67%)	Gaps:	14/195 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMR 68
            ||:||:|.|||||||||:||.|.|||..|||||||||.|..|:|||..:|::|||||.|:|:|||
Zfish    15 YKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMR 79

  Fly    69 DLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKN 133
            :.||:.|.||::|:|:|.:::|..:....:.||||||.:..|||||.||.||...|.:..|.|:.
Zfish    80 EQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKITSEQGRE 144

  Fly   134 LATQFNCAFMETSAK-AKVNVNDIFYDLVRQINKKSPEKKQKKPKKSL-------------CVLL 184
            :|::.:..::||||| ..:||:..|::|||.|.::.||:..||.:|..             ||||
Zfish   145 MASKHSITYIETSAKDPPMNVDKAFHELVRVIRQQIPERGLKKKRKGKWRADRPSASQRLHCVLL 209

Fly 185 184
Zfish 210 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap1	NP_001189023.1	Rap1	3..165	CDD:133375	84/161 (52%)
mrasb	XP_003201047.1	P-loop_NTPase	13..177	CDD:304359	84/161 (52%)
mrasb	XP_003201047.1	small_GTPase	27..179	CDD:197466	76/151 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910