DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12020 and Dnajc21

DIOPT Version :9

Sequence 1:	NP_647662.1	Gene:	CG12020 / 38233	FlyBaseID:	FBgn0035273	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_084322.2	Gene:	Dnajc21 / 78244	MGIID:	1925371	Length:	531	Species:	Mus musculus

Alignment Length:	382	Identity:	85/382 - (22%)
Similarity:	142/382 - (37%)	Gaps:	115/382 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YYAVLDQPRGATKEQITLAYRRLAIRLCPHRDKKDEQDFVPLAQEGRLTHLSPMGEPRQWAYVNM 72
            :|..|...|.|::|::..|||:||:|.  |.||             .|.:.:...|  |:..:..
Mouse     4 HYEALGVRRDASEEELKKAYRKLALRW--HPDK-------------NLDNAAEAAE--QFKLIQA 51

  Fly    73 AFDVLGNDLYRAIYDRFGEAGLFEGVMLPNGYFPPYQYDGDHMKVY------------ERVFGSY 125
            |:|||.:...||.||...||      :|..|....||.|...:..|            ||  |.|
Mouse    52 AYDVLSDPQERAWYDNHREA------LLKGGLDGEYQDDSLDLLHYFTVTCYSGYGDDER--GFY 108

  Fly   126 SPYANVIDAISNPPSLYATRQHGI------GVRSKDASTERIIELSLEEVRTGCVKLMNVWRQEI 184
            :.|..|.:.|:. ..|....:..:      |....|..|  ::.......::.|.:....|::|
Mouse   109 AVYRVVFELIAK-EELECMSEGDVEDFPTFGDSQSDYDT--VVHPFYAHWQSFCTQKNFSWKEE- 169

  Fly   185 VDAKE--SRLEKRKHTLKLNIAPGTTAGTRFCFKEEGDRYPATIPGDIIFIAADKPHPDFERRNQ 247
            .|.::  :|.|||                  ..::|                 :|...|..|:.:
Mouse   170 YDTRQASNRWEKR------------------AMEKE-----------------NKKIRDRARKEK 199

  Fly   248 HDLVYRQSIGLCQAFTGFTFFICTLDRRQLKVVITDVVQPGYTKVVPLEGLPKCRNLDAV---TA 309
            ::|| ||.:.          ||...|:|         || .:.|:|..:...|.|..:.:   ..
Mouse   200 NELV-RQLVA----------FIRKRDKR---------VQ-AHRKLVEEQNAEKARKAEEMRRQQK 243

  Fly   310 IKEANKKVEQFGDLIIEFDYIFPKYLTPHMKHITREFFREF--RKLEIELEEEEERN 364
            :|:| |..||:.    |..::....|...::.:...:.:||  ...|.|:|::|.||
Mouse   244 LKQA-KLAEQYR----EQSWMTMANLEKELQEMEARYEKEFGDGSDENEVEDQEPRN 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12020	NP_647662.1	DnaJ	7..352	CDD:223560	79/368 (21%)
		DnaJ	7..87	CDD:278647	23/78 (29%)
		DnaJ_C	156..335	CDD:199909	33/183 (18%)
Dnajc21	NP_084322.2	DnaJ	3..66	CDD:278647	23/78 (29%)
		DBINO	<181..243	CDD:290603	20/117 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	278..309		8/18 (44%)
		zf-C2H2_jaz	314..339	CDD:288983
		C2H2 Zn finger	316..338	CDD:275371
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..480
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	507..531
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900