DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12020 and Dnajb14

DIOPT Version :9

Sequence 1:	NP_647662.1	Gene:	CG12020 / 38233	FlyBaseID:	FBgn0035273	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001028327.1	Gene:	Dnajb14 / 70604	MGIID:	1917854	Length:	379	Species:	Mus musculus

Alignment Length:	281	Identity:	62/281 - (22%)
Similarity:	95/281 - (33%)	Gaps:	111/281 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DYYAVLDQPRGATKEQITLAYRRLAIRLCPHRDKKDEQDFVPLAQEGRLTHLSPMGEPRQWAYVN 71
            :||.||...:.|..|.:..|||:||::.  |.||..                :| |....:..:.
Mouse   108 NYYEVLGVTKDAGDEDLKKAYRKLALKF--HPDKNH----------------AP-GATDAFKKIG 153

  Fly    72 MAFDVLGNDLYRAIYDRFG--------------------EA--------GLFEGVMLPNG----- 103
            .|:.||.|...|..||..|                    ||        .:|.|...|:|
Mouse   154 NAYAVLSNPEKRKQYDLTGSEEQACNHQNNGRFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSF 218

  Fly   104 ------YFPPYQY-DGDHMKVYERVFGSYSPYANVIDAI-------------SNPP-SLYATRQH 147
                  |...:|: ...|.:..||..|.:|.:..::..|             |||| |||.....
Mouse   219 SNGRAAYSHQHQHRHSGHEREEERADGGFSVFIQLMPIIVLILVSLLSQLMVSNPPYSLYPRSGS 283

  Fly   148 GIGVR------------SKDASTE------RIIELSLEE-----VRTGCVKLMNVW--RQEIVDA 187
            |..::            |||..:|      :.:|.|:||     :|..|      |  ||:..|.
Mouse   284 GQTIKMQTENLGVVYYVSKDFKSEYKGTLLQKVEKSVEEDYVTNIRNNC------WKERQQKTDM 342

  Fly   188 -------KESRLEKRKHTLKL 201
                   ::.:|.::...|.:
Mouse   343 QYAAKVYRDEQLRRKADALSM 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12020	NP_647662.1	DnaJ	7..352	CDD:223560	62/281 (22%)
		DnaJ	7..87	CDD:278647	21/79 (27%)
		DnaJ_C	156..335	CDD:199909	13/66 (20%)
Dnajb14	NP_001028327.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	56..90
		DnaJ	107..>214	CDD:223560	29/124 (23%)
		DnaJ	108..169	CDD:278647	21/79 (27%)
		DUF1977	271..371	CDD:286411	24/99 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900