DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12020 and Dnaja4

DIOPT Version :9

Sequence 1:	NP_647662.1	Gene:	CG12020 / 38233	FlyBaseID:	FBgn0035273	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001344804.1	Gene:	Dnaja4 / 58233	MGIID:	1927638	Length:	426	Species:	Mus musculus

Alignment Length:	433	Identity:	107/433 - (24%)
Similarity:	182/433 - (42%)	Gaps:	121/433 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ELDYYAVLDQPRGATKEQITLAYRRLAIRLCPHRDKKDEQDFVPLAQEGRLTHLSPMGEPRQWAY 69
            |..||.:|.....|:.|:|..|||:||::.  |.||..::                 ||  ::..
Mouse    33 ETQYYDILGVKPSASPEEIKKAYRKLALKY--HPDKNPDE-----------------GE--KFKL 76

  Fly    70 VNMAFDVLGNDLYRAIYDRFGEAGLFEGVMLPNGYFPPYQYDGDHMKVYERVFGSYSPYA----- 129
            ::.|::||.:...|.|||:.||..:.||......:..|       |.:::..||......
Mouse    77 ISQAYEVLSDPKKRDIYDQGGEQAIKEGGSGSPSFSSP-------MDIFDMFFGGGGRMTRERRG 134

  Fly   130 -NVIDAIS-NPPSLY-------ATRQHGI-----GVRSKDASTER------------IIELS--- 165
             ||:..:| ....||       |.:::.|     |:..|..|.|:            |.::.
Mouse   135 KNVVHQLSVTLEDLYNGITKKLALQKNVICEKCEGIGGKKGSVEKCPLCKGRGMQVHIQQIGPGM 199

  Fly   166 LEEVRTGCVKLMNVWRQEIVDAKE-------SRLEKRKHTLKLNIAPGTTAGTRFCFKEEGDRYP 223
            :::::|.|::...  :.|.::.|:       :::.:.|..:::::..|...|.:..|..|||:.|
Mouse   200 VQQIQTVCIECKG--QGERINPKDRCENCSGAKVTREKKIIEVHVEKGMKDGQKILFHGEGDQEP 262

  Fly   224 ATIPGDIIFIAADKPHPDFERRNQHDLVYRQSIGLCQAFTGFTFFICTLDRRQLKVVIT----DV 284
            ...|||:|.:...|.|..|:||.| ||:.:..|.|.:|..||...|.|||.|.|  ||:    :|
Mouse   263 ELDPGDVIIVLDQKDHSVFQRRGQ-DLIMKMKIQLSEALCGFKKTIKTLDDRVL--VISSKSGEV 324

  Fly   285 VQPGYTKVVPLEGLPKCRNLDAVTAIKEANKKVEQFGDLIIEFDYIFPK--------------YL 335
            ::.|..|.:..||:|             ..|...:.|.:||:|..:||:              .|
Mouse   325 IKHGDLKCIRNEGMP-------------IYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALL 376

  Fly   336 TPHMK-HIT--------REF------FREFRKLEIELEEEEER 363
            .|..| .||        :||      :|:.|: ..|.::||.|
Mouse   377 PPRQKVRITDDMDQVELKEFNPNEQSWRQHRE-AYEEDDEEPR 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12020	NP_647662.1	DnaJ	7..352	CDD:223560	101/418 (24%)
		DnaJ	7..87	CDD:278647	21/79 (27%)
		DnaJ_C	156..335	CDD:199909	53/218 (24%)
Dnaja4	NP_001344804.1	DnaJ	15..423	CDD:333066	107/433 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880