Protein Alignment CG12020 and DNAJA4

DIOPT Version :10

• Sequence 1: NP_647662.1
• Gene: CG12020 / 38233
• FlyBaseID: FBgn0035273
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: XP_047288792.1
• Gene: DNAJA4 / 55466
• HGNCID: 14885
• Length: 444
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 114/437 - (26%)
• Similarity: 186/437 - (42%)
• Gaps: 116/437 - (26%)

  Fly     5 ELDYYAVLDQPRGATKEQITLAYRRLAIRLCPHRDKKDEQDFVPLAQEGRLTHLSPMGEPRQWAY 69
            |..||.:|.....|:.|:|..|||:||::.  |.||..::     .::|. .||.|  :...::|
Human    33 ETQYYDILGVKPSASPEEIKKAYRKLALKY--HPDKNPDE-----GEKGH-GHLQP--DISLYSY 87

  Fly    70 -------VNMAFDVLGNDLYRAIYDRFGEAGLFEGVMLPNGYFPPYQYDGDHMKVYERVFGSYSP 127
                   ::.|::||.:...|.:||:.||..:.||......:..|       |.:::..||....
Human    88 SGFSFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFSSP-------MDIFDMFFGGGGR 145

  Fly   128 YA------NVIDAIS-NPPSLY-------ATRQHGI-----GVRSKDASTE-------RIIELSL 166
            .|      ||:..:| ....||       |.:::.|     ||..|..|.|       |.:::.:
Human   146 MARERRGKNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQIHI 210

  Fly   167 EEVRTGCVKLMNV------WRQEIVDAKE-------SRLEKRKHTLKLNIAPGTTAGTRFCFKEE 218
            :::..|.|:.:..      .:.|.::.|:       :::.:.|..:::::..|...|.:..|..|
Human   211 QQIGPGMVQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKDGQKILFHGE 275

  Fly   219 GDRYPATIPGDIIFIAADKPHPDFERRNQHDLVYRQSIGLCQAFTGFTFFICTLDRRQLKVVIT- 282
            ||:.|...|||:|.:...|.|..|:||. |||:.:..|.|.:|..||...|.|||.|.|  |||
Human   276 GDQEPELEPGDVIIVLDQKDHSVFQRRG-HDLIMKMKIQLSEALCGFKKTIKTLDNRIL--VITS 337

  Fly   283 ---DVVQPGYTKVVPLEGLPKCRNLDAVTAIKEANKKVEQFGDLIIEFDYIFPK----------- 333
               :|::.|..:.|..||:|             ..|...:.|.|||:|..|||:
Human   338 KAGEVIKHGDLRCVRDEGMP-------------IYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQ 389

  Fly   334 ---YLTPHMK-HIT--------REF------FREFRKLEIELEEEEE 362
               .|.|..| .||        :||      :|:.|    |..||:|
Human   390 LEALLPPRQKVRITDDMDQVELKEFCPNEQNWRQHR----EAYEEDE 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12020	NP_647662.1	PRK14289	7..299	CDD:237660	90/341 (26%)
		DnaJ_C	156..335	CDD:199909	56/216 (26%)
DNAJA4	XP_047288792.1	PTZ00037	15..441	CDD:240236	114/437 (26%)