Protein Alignment CG12020 and DNAJA4

DIOPT Version :9

• Sequence 1: NP_647662.1
• Gene: CG12020 / 38233
• FlyBaseID: FBgn0035273
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_061072.3
• Gene: DNAJA4 / 55466
• HGNCID: 14885
• Length: 426
• Species: Homo sapiens
• Alignment Length: 430
• Identity: 111/430 - (25%)
• Similarity: 180/430 - (41%)
• Gaps: 120/430 - (27%)

  Fly     5 ELDYYAVLDQPRGATKEQITLAYRRLAIRLCPHRDKKDEQDFVPLAQEGRLTHLSPMGEPRQWAY 69
            |..||.:|.....|:.|:|..|||:||::.  |.||..::                 ||  ::..
Human    33 ETQYYDILGVKPSASPEEIKKAYRKLALKY--HPDKNPDE-----------------GE--KFKL 76

  Fly    70 VNMAFDVLGNDLYRAIYDRFGEAGLFEGVMLPNGYFPPYQYDGDHMKVYERVFGSYSPYA----- 129
            ::.|::||.:...|.:||:.||..:.||......:..|       |.:::..||.....|
Human    77 ISQAYEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFSSP-------MDIFDMFFGGGGRMARERRG 134

  Fly   130 -NVIDAIS-NPPSLY-------ATRQHGI-----GVRSKDASTE-------RIIELSLEEVRTGC 173
             ||:..:| ....||       |.:::.|     ||..|..|.|       |.:::.::::..|.
Human   135 KNVVHQLSVTLEDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQIHIQQIGPGM 199

  Fly   174 VKLMNV------WRQEIVDAKE-------SRLEKRKHTLKLNIAPGTTAGTRFCFKEEGDRYPAT 225
            |:.:..      .:.|.::.|:       :::.:.|..:::::..|...|.:..|..|||:.|..
Human   200 VQQIQTVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKDGQKILFHGEGDQEPEL 264

  Fly   226 IPGDIIFIAADKPHPDFERRNQHDLVYRQSIGLCQAFTGFTFFICTLDRRQLKVVIT----DVVQ 286
            .|||:|.:...|.|..|:||. |||:.:..|.|.:|..||...|.|||.|.|  |||    :|::
Human   265 EPGDVIIVLDQKDHSVFQRRG-HDLIMKMKIQLSEALCGFKKTIKTLDNRIL--VITSKAGEVIK 326

  Fly   287 PGYTKVVPLEGLPKCRNLDAVTAIKEANKKVEQFGDLIIEFDYIFPK--------------YLTP 337
            .|..:.|..||:|             ..|...:.|.|||:|..|||:              .|.|
Human   327 HGDLRCVRDEGMP-------------IYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQLEALLPP 378

  Fly   338 HMK-HIT--------REF------FREFRKLEIELEEEEE 362
            ..| .||        :||      :|:.|    |..||:|
Human   379 RQKVRITDDMDQVELKEFCPNEQNWRQHR----EAYEEDE 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12020	NP_647662.1	DnaJ	7..352	CDD:223560	105/416 (25%)
		DnaJ	7..87	CDD:278647	20/79 (25%)
		DnaJ_C	156..335	CDD:199909	56/216 (26%)
DNAJA4	NP_061072.3	PTZ00037	15..423	CDD:240236	111/430 (26%)
		DnaJ	36..94	CDD:278647	20/78 (26%)
		DnaJ_C	135..361	CDD:199909	66/241 (27%)
		DnaJ_zf	164..230	CDD:199908	10/65 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.880