DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12020 and DNAJB9

DIOPT Version :9

Sequence 1:	NP_647662.1	Gene:	CG12020 / 38233	FlyBaseID:	FBgn0035273	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_036460.1	Gene:	DNAJB9 / 4189	HGNCID:	6968	Length:	223	Species:	Homo sapiens

Alignment Length:	149	Identity:	32/149 - (21%)
Similarity:	57/149 - (38%)	Gaps:	24/149 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YYAVLDQPRGATKEQITLAYRRLAIRLCPHRDKKDEQDFVPLAQEGRLTHLSPMGEPRQWAYVNM 72
            ||.:|..|:.|::.||..|:.:||::..|.::|..:       .|.:...::...|....|....
Human    27 YYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPD-------AEAKFREIAEAYETLSDANRRK 84

  Fly    73 AFDVLGNDLYRAIYDRFGEAGLFEGVMLPN--GYFPPYQYDGDHMKVYERVFGSYSPYANVIDAI 135
            .:|.||:..:.:...:.|....||.....|  ..|..:.:.|.:...     ||...:.|
Human    85 EYDTLGHSAFTSGKGQRGSGSSFEQSFNFNFDDLFKDFGFFGQNQNT-----GSKKRFEN----- 139

  Fly   136 SNPPSLYATRQHGIGVRSK 154
                 .:.|||.|...|.:
Human   140 -----HFQTRQDGGSSRQR 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12020	NP_647662.1	DnaJ	7..352	CDD:223560	32/149 (21%)
		DnaJ	7..87	CDD:278647	18/78 (23%)
		DnaJ_C	156..335	CDD:199909
DNAJB9	NP_036460.1	type 2 signal-anchor for ER localization	7..23
		DnaJ	26..>136	CDD:333066	26/120 (22%)
		Divergent targeting domain. /evidence=ECO:0000250\|UniProtKB:Q9QYI6	91..223		14/78 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900