DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12020 and DNAJC18

DIOPT Version :9

Sequence 1:	NP_647662.1	Gene:	CG12020 / 38233	FlyBaseID:	FBgn0035273	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_689899.1	Gene:	DNAJC18 / 202052	HGNCID:	28429	Length:	358	Species:	Homo sapiens

Alignment Length:	162	Identity:	42/162 - (25%)
Similarity:	68/162 - (41%)	Gaps:	36/162 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DYYAVLDQPRGATKEQITLAYRRLAIRLCPHRDKKDEQDFVPLAQEGRLTHLSPMGEPRQWAYVN 71
            :||.:|...|.|:.|::..|||:||::.  |.||                :.:| |....:..:.
Human    82 NYYEILGVSRDASDEELKKAYRKLALKF--HPDK----------------NCAP-GATDAFKAIG 127

  Fly    72 MAFDVLGNDLYRAIYDRFGEAGLFEGVML------PNGYFPPYQYDGDHMKVYERVFGSYSPYAN 130
            .||.||.|...|..||.:|:    |.|..      |..|:..::.|....:::...||.:.|..|
Human   128 NAFAVLSNPDKRLRYDEYGD----EQVTFTAPRARPYNYYRDFEADITPEELFNVFFGGHFPTGN 188

  Fly   131 VIDAISN--PPSLYATRQHGIGVRSKDASTER 160
             |...||  ..:.|..|:|    |.:...|::
Human   189 -IHMFSNVTDDTYYYRRRH----RHERTQTQK 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12020	NP_647662.1	DnaJ	7..352	CDD:223560	42/162 (26%)
		DnaJ	7..87	CDD:278647	22/79 (28%)
		DnaJ_C	156..335	CDD:199909	1/5 (20%)
DNAJC18	NP_689899.1	DnaJ	82..143	CDD:278647	22/79 (28%)
DNAJC18	NP_689899.1	DUF1977	250..350	CDD:286411
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900