DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12020 and DNAJB8

DIOPT Version :9

Sequence 1:	NP_647662.1	Gene:	CG12020 / 38233	FlyBaseID:	FBgn0035273	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_699161.1	Gene:	DNAJB8 / 165721	HGNCID:	23699	Length:	232	Species:	Homo sapiens

Alignment Length:	136	Identity:	35/136 - (25%)
Similarity:	57/136 - (41%)	Gaps:	40/136 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DYYAVLDQPRGATKEQITLAYRRLAIRLCPHR--DKKDEQDFVPLAQEGRLTHLSPMGEPRQWAY 69
            :||.||.....|:.|.|..|||:||:|..|.:  |.|:|.:                   :::..
Human     3 NYYEVLGVQASASPEDIKKAYRKLALRWHPDKNPDNKEEAE-------------------KKFKL 48

  Fly    70 VNMAFDVLGNDLYRAIYDRFG----EAGLFEGVMLPNGYFPPYQ--YDGDHM-----KVYERVFG 123
            |:.|::||.:...|::|||.|    .||        .|...||.  :|..:.     .::...||
Human    49 VSEAYEVLSDSKKRSLYDRAGCDSWRAG--------GGASTPYHSPFDTGYTFRNPEDIFREFFG 105

  Fly   124 SYSPYA 129
            ...|::
Human   106 GLDPFS 111

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12020	NP_647662.1	DnaJ	7..352	CDD:223560	35/136 (26%)
		DnaJ	7..87	CDD:278647	22/81 (27%)
		DnaJ_C	156..335	CDD:199909
DNAJB8	NP_699161.1	DnaJ	3..>106	CDD:223560	33/129 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810